Evidence map›Paper›PMID 19463223›Full record

ReviewCurrent gastroenterology reports2009

Current perspectives on pediatric intestinal transplantation.

George V Mazariegos, Robert H Squires, Rakesh K Sindhi

Open access · bronzeAbstract readReview
PubMed Publisher
In one paragraph

Review in Current gastroenterology reports, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Review
  3. Race affects outcome among infants with intestinal failure.Journal of pediatric gastroenterology and nutrition · 2014
    Article
  4. Short bowel syndrome in the NICU.Clinics in perinatology · 2013
    Review
  5. Recent advances in small bowel diseases: Part II.World journal of gastroenterology · 2012
    Review
  6. Living donor intestinal transplant using a standardized technique: first report from India.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2012
    Article
  7. Review
  8. Psychiatric issues in pediatric organ transplantation.Child and adolescent psychiatric clinics of North America · 2010
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

George V MazariegosChildren's Hospital of Pittsburgh, Pittsburgh, PA 15213, USA. george.mazariegos@chp.edu
Robert H Squires
Rakesh K Sindhi
Children's Hospital of Pittsburgh · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Irreversible intestinal failure in children is predominantly caused by surgical conditions such as volvulus, necrotizing enterocolitis, and gastroschisis. Functional intestinal failure from motility disorders such as intestinal pseudo-obstruction or enterocyte dysfunction with microvillus inclusion disease also may require intestine replacement. Approved indications for intestinal transplantation include liver dysfunction, loss of major venous access, frequent central line-related sepsis, and recurrent episodes of severe dehydration despite intravenous fluid management. Surgical options include transplantation of the isolated intestine, combined liver-intestine transplantation, or multivisceral transplantation of the stomach, duodenum, pancreas, and small bowel (with or without the liver). Immunosuppression for intestinal transplantation is based on tacrolimus therapy, often with induction immunosuppression using antilymphocyte antibodies (eg, antithymocyte antibody and alemtuzumab). Experience at centers of excellence demonstrates 1- and 5-year patient survival rates of 95% and 77%, respectively, with ongoing investigations focusing on lowering long-term causes of graft loss such as chronic rejection.

Indexed as

ChildGraft RejectionHumansIntestinal DiseasesIntestinesTreatment Outcome

Identifiers

PMID19463223
OpenAlexW2050775751

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.