ArticleAJNR. American journal of neuroradiology2009
Dural ectasia in Marfan syndrome: a case control study.
Article in AJNR. American journal of neuroradiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 58 citations in OpenAlex.
- Duropathies as Unifying Concept-Part Two: A Narrative Overview of Clinical and Neuroradiological Features.Neurology international · 2026Review
- New CT-based dural ectasia criteria using machine learning to diagnose Marfan and Loeys-Dietz syndromes.European heart journal. Imaging methods and practice · 2026Article
- Quantitative measurement of dural ectasia: associations with clinical and genetic characteristics in Marfan syndrome.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024Article
- MRI-Derived Dural Sac and Lumbar Vertebrae 3D Volumetry Has Potential for Detection of Marfan Syndrome.Diagnostics (Basel, Switzerland) · 2024Article
- The Musculoskeletal Manifestations of Marfan Syndrome: Diagnosis, Impact, and Management.Current rheumatology reports · 2021Review
- Physiological pseudo-thickened cauda equina associated with dural sac dilatation on magnetic resonance imaging.The neuroradiology journal · 2021Article
- Pathophysiology and Pathogenesis of Marfan Syndrome.Advances in experimental medicine and biology · 2021Review
- Epidural Anesthesia for Cesarean Section in a Pregnant Woman with Marfan Syndrome and Dural Ectasia.Case reports in obstetrics and gynecology · 2017Article
- Sagittal Normal Limits of Lumbosacral Spine in a Large Adult Population: A Quantitative Magnetic Resonance Imaging Analysis.Journal of clinical imaging science · 2017Article
- Epidural analgesia complicated by dural ectasia in the Marfan syndrome.Proceedings (Baylor University. Medical Center) · 2016Article
- Standardization and validation of a novel and simple method to assess lumbar dural sac size.Clinical radiology · 2015Article
- Perspectives on the revised Ghent criteria for the diagnosis of Marfan syndrome.The application of clinical genetics · 2015Review
- Spinal imaging features in Japanese patients with Marfan syndrome: a case-control study.Japanese journal of radiology · 2014Article
- Noninvasive diagnosis and management of spontaneous intracranial hypotension in patients with marfan syndrome: Case Report and Review of the Literature.Surgical neurology international · 2014Article
- Prevalence of dural ectasia in Loeys-Dietz syndrome: comparison with Marfan syndrome and normal controls.PloS one · 2013Article
- Preventing the aortic complications of Marfan syndrome: a case-example of translational genomic medicine.British journal of clinical pharmacology · 2011Review
- Marsupialization and distal obliteration of a lumbosacral dural ectasia in a nonsyndromic, adult patient.Journal of craniovertebral junction & spineArticle
- Pelvic dural ectasia leading to bilateral ureteric obstruction in the pediatric patient.Canadian Urological Association journal = Journal de l'Association des urologues du CanadaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeDural ectasia (DE) is one of the major criteria of Marfan syndrome (MFS). Our aim was to establish the prevalence of DE in an adult population fulfilling the Ghent criteria for MFS and to assess definitions of DE. MATERIALS AND
methodsOne hundred five adults with suspected MFS were included. MR imaging at 1.5T was performed unless contraindicated; then CT was obtained. Lumbosacral anteroposterior vertebral body diameters (VBD) and dural sac diameters (DSD) were measured. Dural sac ratios (DSR = DSD/VBD) at levels L3 through S1 were calculated. Anterior meningoceles, herniations of nerve root sleeves, and scalloping were characterized. One hundred one sex- and age-matched patients were included as controls.
resultsWe identified 3 patient groups: 1) fulfilling Ghent criteria independent of DE (n = 73), 2); fulfilling Ghent criteria dependent on DE (n = 14), and 3); and suspected MFS, not fulfilling Ghent criteria (n = 18). DE was found in 86% of group 1. At levels L4-S1, mean DSRs were significantly higher in group 1 than in group 3 and controls (P < .001). Herniations of the nerve root sleeves were present in 73% in group 1 versus 1% in controls. Anterior meningoceles were found in 37% and 14% in groups 1 and 2, respectively, but not in group 3 or controls.
conclusionsThe diagnosis of DE on MR imaging or CT should be based on the presence of at least 1 of the following criteria: anterior meningoceles or nerve root sleeve herniation, DSD at S1 or below larger than DSD at L4, and DSR at S1 >0.59.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.