ArticleEuropean journal of applied physiology2009
Association between ACE D allele and elite short distance swimming.
Article in European journal of applied physiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 82 citations in OpenAlex.
- The association of sport performance with ACE and ACTN3 genetic polymorphisms: a systematic review and meta-analysis.PloS one · 2013Pooled it
- Pooled it
- Muscle Work and Its Relationship withGenes · 2021Trial
- Association between ACTN3 (R577X), ACE (I/D), BDKRB2 (-9/+9), and AGT (M268T) polymorphisms and performance phenotypes in Brazilian swimmers.BMC sports science, medicine & rehabilitation · 2024Article
- Genes and Athletic Performance: The 2023 Update.Genes · 2023Review
- Genetics and sports performance: the present and future in the identification of talent for sports based on DNA testing.European journal of applied physiology · 2022Review
- Genetic Markers Associated with Power Athlete Status.Journal of human kinetics · 2019Article
- Performance prediction models based on anthropometric, genetic and psychological traits of Croatian sprinters.Biology of sport · 2019Article
- The Potential Role of Genetic Markers in Talent Identification and Athlete Assessment in Elite Sport.Sports (Basel, Switzerland) · 2018Review
- Genetic variation and exercise-induced muscle damage: implications for athletic performance, injury and ageing.European journal of applied physiology · 2016Review
- The Great British Medalists Project: A Review of Current Knowledge on the Development of the World's Best Sporting Talent.Sports medicine (Auckland, N.Z.) · 2016Review
- Distribution of Angiotensin-1 Converting Enzyme Insertion/Deletion and α-Actinin-3 Codon 577 Polymorphisms in Turkish Male Soccer Players.Genetics & epigenetics · 2015Article
- Genetic basis of interindividual susceptibility to cancer cachexia: selection of potential candidate gene polymorphisms for association studies.Journal of genetics · 2014Review
- Interaction Between ACE I/D and ACTN3 R557X Polymorphisms in Polish Competitive Swimmers.Journal of human kinetics · 2014Article
- Bdkrb2 gene -9/+9 polymorphism and swimming performance.Biology of sport · 2014Article
- Evaluation of ACE gene I/D polymorphism in Iranian elite athletes.Advanced biomedical research · 2014Article
- The influence of ACE ID and ACTN3 R577X polymorphisms on lower-extremity function in older women in response to high-speed power training.BMC geriatrics · 2013Article
- Genes for elite power and sprint performance: ACTN3 leads the way.Sports medicine (Auckland, N.Z.) · 2013Review
- The genetics of sports injuries and athletic performance.Muscles, ligaments and tendons journal · 2013Review
- ACE I/D, ACTN3 R577X, PPARD T294C and PPARGC1A Gly482Ser polymorphisms and physical fitness in Taiwanese late adolescent girls.The journal of physiological sciences : JPS · 2012Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The influence of ACE gene on athletic performance has been widely explored, and most of the published data refers to an I/D polymorphism leading to the presence (I allele) or absence (D allele) of a 287-bp sequence in intron 16, determining ACE activity in serum and tissues. A higher I allele frequency has been reported among elite endurance athletes, while the D allele was more frequent among those engaged in more power-orientated sports. However, on competitive swimming, the reproducibility of such associations is controversial. We thus compared the ACE genotype of elite swimmers with that of non-elite swimming cohort and of healthy control subjects. We thus sought an association of the ACE genotype of elite swimmers with their competitive distance. 39 Portuguese Olympic swimming candidates were classified as: short (<200 m) and middle (400-1,500 m) distance swimmers, respectively. A group of 32 non-elite swimmers were studied and classified as well, and a control group (n = 100) was selected from the Portuguese population. Chelex 100 was used for DNA extraction and genotype was determined by PCR-RFLP methods. We found that ACE genotype distribution and allelic frequency differs significantly by event distance only among elite swimmers (P < or = 0.05). Moreover, the allelic frequency of the elite short distance swimmers differed significantly from that of the controls (P = 0.021). No associations were found between middle distance swimmers and controls. Our results seem to support an association between the D allele and elite short distance swimming.
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