ArticleBiotechnology letters2009
Deletion of methylglyoxal synthase gene (mgsA) increased sugar co-metabolism in ethanol-producing Escherichia coli.
Article in Biotechnology letters, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 122 citations in OpenAlex.
- Coordinated Regulation of Glutamate-GABA Flux Enables High-Titre GABA Production in Enterococcus faecium.Applied biochemistry and biotechnology · 2026Article
- Efficient synthesis of optically pure D-lactate from mixed sugars by engineeredBiodesign research · 2026Article
- The deficiency of methylglyoxal synthase promotes cell proliferation inPlant biotechnology (Tokyo, Japan) · 2024Article
- Efficient production of 1,2,4-butanetriol from corn cob hydrolysate by metabolically engineered Escherichia coli.Microbial cell factories · 2024Article
- Adaptation on xylose improves glucose-xylose co-utilization and ethanol production in a carbon catabolite repression (CCR) compromised ethanologenic strain.Microbial cell factories · 2022Article
- Article
- Principles and practice of designing microbial biocatalysts for fuel and chemical production.Journal of industrial microbiology & biotechnology · 2022Review
- The Physiological Responses ofMicroorganisms · 2020Article
- Engineering of glycerol utilization in Pseudomonas chlororaphis GP72 for enhancing phenazine-1-carboxylic acid production.World journal of microbiology & biotechnology · 2020Article
- Catabolic Division of Labor Enhances Production of D-Lactate and Succinate From Glucose-Xylose Mixtures in EngineeredFrontiers in bioengineering and biotechnology · 2020Article
- Systems Metabolic Engineering of Escherichia coli Improves Coconversion of Lignocellulose-Derived Sugars.Biotechnology journal · 2019Article
- Improved ethanol productivity from lignocellulosic hydrolysates by Escherichia coli with regulated glucose utilization.Microbial cell factories · 2018Article
- Production of naringenin from D-xylose with co-culture ofEngineering in life sciences · 2017Article
- Experimental evolution reveals an effective avenue to release catabolite repression via mutations in XylR.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Plasmidic Expression of nemA and yafC* Increased Resistance of Ethanologenic Escherichia coli LY180 to Nonvolatile Side Products from Dilute Acid Treatment of Sugarcane Bagasse and Artificial Hydrolysate.Applied and environmental microbiology · 2016Article
- Engineering Sugar Utilization and Microbial Tolerance toward Lignocellulose Conversion.Frontiers in bioengineering and biotechnology · 2015Review
- Metabolic Engineering of Escherichia coli for Production of Mixed-Acid Fermentation End Products.Frontiers in bioengineering and biotechnology · 2014Review
- Complex physiology and compound stress responses during fermentation of alkali-pretreated corn stover hydrolysate by an Escherichia coli ethanologen.Applied and environmental microbiology · 2012Article
- Supplementation of intracellular XylR leads to coutilization of hemicellulose sugars.Applied and environmental microbiology · 2012Article
- Optical mapping and sequencing of the Escherichia coli KO11 genome reveal extensive chromosomal rearrangements, and multiple tandem copies of the Zymomonas mobilis pdc and adhB genes.Journal of industrial microbiology & biotechnology · 2012Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The use of lignocellulose as a source of sugars for bioproducts requires the development of biocatalysts that maximize product yields by fermenting mixtures of hexose and pentose sugars to completion. In this study, we implicate mgsA encoding methylglyoxal synthase (and methylglyoxal) in the modulation of sugar metabolism. Deletion of this gene (strain LY168) resulted in the co-metabolism of glucose and xylose, and accelerated the metabolism of a 5-sugar mixture (mannose, glucose, arabinose, xylose and galactose) to ethanol.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.