Evidence map›Paper›PMID 19458491›Full record

ReviewPrion

The centrosome and asymmetric cell division.

Yukiko M Yamashita

Open access · bronzeAbstract readReview
In one paragraph

Review in Prion. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 34 citations in OpenAlex.

  1. Isolation of Mitotic Centrosomes from Cultured Human Cells.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  2. Modulating DNA Polα Enhances Cell Reprogramming Across Species.bioRxiv : the preprint server for biology · 2024
    Article
  3. Cellular senescence, rejuvenation and potential immortality.Proceedings. Biological sciences · 2022
    Review
  4. Review
  5. Adipose Stem Cell Translational Applications: From Bench-to-Bedside.International journal of molecular sciences · 2018
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. When fate follows age: unequal centrosomes in asymmetric cell division.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2014
    Review
  13. Article
  14. Asymmetric cell division of stem cells in the lung and other systems.Frontiers in cell and developmental biology · 2014
    Review
  15. Review
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Yukiko M YamashitaLife Sciences Institute, Center for Stem Cell Biology, Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109-2216, USA. yukikomy@umich.edu
University of Michigan–Ann Arbor · US

Funding

Physiological regulation and function of asymmetric stem cell divisionR01GM086481 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI YAMASHITA, YUKIKO · 2009 to 2013
$1.7M
NIGMS NIH HHS R01 GM086481NIGMS NIH HHS R01GM086481-01
6 · The paper itself

Abstract

Asymmetric stem cell division is a mechanism widely employed by the cell to maintain tissue homeostasis, resulting in the production of one stem cell and one differentiating cell. However, asymmetric cell division is not limited to stem cells and is widely observed even in unicellular organisms as well as in cells that make up highly complex tissues. In asymmetric cell division, cells must organize their intracellular components along the axis of asymmetry (sometimes in the context of extracellular architecture). Recent studies have described cell asymmetry in many cell types and in many cases such asymmetry involves the centrosome (or spindle pole body in yeast) as the center of cytoskeleton organization. In this review, I summarize recent discoveries in cellular polarity that lead to an asymmetric outcome, with a focus on centrosome function.

Indexed as

AnimalsCell DivisionCell PolarityCentrosomeHumansModels, Biological

Identifiers

PMID19458491
PMCPMC2712604
OpenAlexW1996779008

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.