ArticleThe Journal of biological chemistry2009
Participation of Xenopus Elr-type proteins in vegetal mRNA localization during oogenesis.
Article in The Journal of biological chemistry, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 33 citations in OpenAlex.
- Article
- ELAVL1 and ELAVL4 are required for Musashi-dependent translational activation.bioRxiv : the preprint server for biology · 2026Article
- Germ plasm dynamics during oogenesis and early embryonic development in Xenopus and zebrafish.Molecular reproduction and development · 2024Review
- Remnants of the Balbiani body are required for formation of RNA transport granules iniScience · 2022Article
- L-bodies are RNA-protein condensates driving RNA localization inMolecular biology of the cell · 2021Article
- Using Morpholinos to Control Gene Expression.Current protocols in nucleic acid chemistry · 2017Article
- A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.eLife · 2015Article
- Global analysis of asymmetric RNA enrichment in oocytes reveals low conservation between closely related Xenopus species.Molecular biology of the cell · 2015Article
- An oocyte-specific ELAVL2 isoform is a translational repressor ablated from meiotically competent antral oocytes.Cell cycle (Georgetown, Tex.) · 2014Article
- RNA localization in Xenopus oocytes uses a core group of trans-acting factors irrespective of destination.RNA (New York, N.Y.) · 2013Article
- Myelin basic protein synthesis is regulated by small non-coding RNA 715.EMBO reports · 2012Article
- Heterogeneous nuclear ribonucleoprotein (hnRNP) F is a novel component of oligodendroglial RNA transport granules contributing to regulation of myelin basic protein (MBP) synthesis.The Journal of biological chemistry · 2012Article
- New insights into the regulation of RNP granule assembly in oocytes.International review of cell and molecular biology · 2012Review
- Elr-type proteins protect Xenopus Dead end mRNA from miR-18-mediated clearance in the soma.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- RNA Localization in the Vertebrate Oocyte: Establishment of Oocyte Polarity and Localized mRNA Assemblages.Results and problems in cell differentiationReview
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Directional transport of specific mRNAs is of primary biological relevance. In Xenopus oocytes, mRNA localization to the vegetal pole is important for germ layer formation and germ cell development. Using a biochemical approach, we identified Xenopus Elr-type proteins, homologs of the Hu/ELAV proteins, as novel components of the vegetal mRNA localization machinery. They bind specifically to the localization elements of several different vegetally localizing Xenopus mRNAs, and they are part of one RNP together with other localization proteins, such as Vg1RBP and XStaufen 1. Blocking Elr-type protein binding by either localization element mutagenesis or antisense morpholino oligonucleotide-mediated masking of their target RNA structures, as well as overexpression of wild type and mutant ElrB proteins, interferes with vegetal localization in Xenopus oocytes.
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