ArticleBMC genomics2009
Recent dermatophyte divergence revealed by comparative and phylogenetic analysis of mitochondrial genomes.
Article in BMC genomics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- A Comparative Description of Dermatophyte Genomes: A State-of-the-Art Review.Mycopathologia · 2023Pooled it
- Haplotype-resolved genomes of Trichophyton mentagrophytes and Trichophyton tonsurans.Scientific data · 2025Article
- Phylogenetic and evolutionary insights from 30 newly-assembledIMA fungus · 2025Article
- Current Topics in Dermatophyte Classification and Clinical Diagnosis.Pathogens (Basel, Switzerland) · 2022Review
- An ancient haplotype containing antimicrobial peptide gene variants is associated with severe fungal skin disease in Persian cats.PLoS genetics · 2022Article
- Mitochondrial genomes of the human pathogens Coccidioides immitis and Coccidioides posadasii.G3 (Bethesda, Md.) · 2021Article
- Comparative Analyses of Mitochondrial Genomes Provide Evolutionary Insights Into Nematode-Trapping Fungi.Frontiers in microbiology · 2020Article
- Mobile genetic elements explain size variation in the mitochondrial genomes of four closely-related Armillaria species.BMC genomics · 2019Article
- Insight into the draft whole-genome sequence of the dermatophyte Arthroderma vanbreuseghemii.Scientific reports · 2018Article
- Phylogeny of dermatophytes with genomic character evaluation of clinically distinctStudies in mycology · 2018Article
- Fungi that Infect Humans.Microbiology spectrum · 2017Review
- Molecular Markers Useful for Intraspecies Subtyping and Strain Differentiation of Dermatophytes.Mycopathologia · 2017Article
- Intron Derived Size Polymorphism in the Mitochondrial Genomes of Closely Related Chrysoporthe Species.PloS one · 2016Article
- Computational analysis of conserved coil functional residues in the mitochondrial genomic sequences of dermatophytes.Bioinformation · 2016Article
- Analysis of the complete mitochondrial genome of Pochonia chlamydosporia suggests a close relationship to the invertebrate-pathogenic fungi in Hypocreales.BMC microbiology · 2015Article
- The spectrum of fungi that infects humans.Cold Spring Harbor perspectives in medicine · 2014Review
- High variability of mitochondrial gene order among fungi.Genome biology and evolution · 2014Article
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- Mitochondrial genome evolution in species belonging to the Phialocephala fortinii s.l. - Acephala applanata species complex.BMC genomics · 2012Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundDermatophytes are fungi that cause superficial infections of the skin, hair, and nails. They are the most common agents of fungal infections worldwide. Dermatophytic fungi constitute three genera, Trichophyton, Epidermophyton, and Microsporum, and the evolutionary relationships between these genera are epidemiologically important. Mitochondria are considered to be of monophyletic origin and mitochondrial sequences offer many advantages for phylogenetic studies. However, only one complete dermatophyte mitochondrial genome (E. floccosum) has previously been determined.
resultsThe complete mitochondrial DNA sequences of five dermatophyte species, T. rubrum (26,985 bp), T. mentagrophytes (24,297 bp), T. ajelloi (28,530 bp), M. canis (23,943 bp) and M. nanum (24,105 bp) were determined. These were compared to the E. floccosum sequence. Mitochondrial genomes of all 6 species were found to harbor the same set of genes arranged identical order indicating that these dermatophytes are closely related. Genome size differences were largely due to variable lengths of non-coding intergenic regions and the presence/absence of introns. Phylogenetic analyses based on complete mitochondrial genomes reveals that the divergence of the dermatophyte clade was later than of other groups of pathogenic fungi.
conclusionThis is the first systematic comparative genomic study on dermatophytes, a highly conserved and recently-diverged lineage of ascomycota fungi. The data reported here provide a basis for further exploration of interrelationships between dermatophytes and will contribute to the study of mitochondrial evolution in higher fungi.
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