ReviewAnalytical and bioanalytical chemistry2009
Immunomodulation by food: promising concept for mitigating allergic disease?
Review in Analytical and bioanalytical chemistry, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 78 citations in OpenAlex.
- Immunomodulatory effects of a probiotic drink containing Lactobacillus casei Shirota in healthy older volunteers.European journal of nutrition · 2013Trial
- Ingestion of micronutrient fortified breakfast cereal has no influence on immune function in healthy children: a randomized controlled trial.Nutrition journal · 2011Trial
- In Vivo Acute Toxicity and Immunomodulation Assessment of a Novel Nutraceutical in Mice.Pharmaceutics · 2023Article
- Children with Delayed-Type Cow's Milk Protein Allergy May Be at a Significant Risk of Developing Immediate Allergic Reactions Upon Re-introduction.Journal of asthma and allergy · 2023Article
- The Biological Effects of Novel Nutraceuticals with Curcuminoids and Other Plant-Derived Immunomodulators and Pre-Probiotics.Pharmaceutics · 2021Article
- Review
- Polyphenols as promising biologically active substances for preventing SARS-CoV-2: A review with research evidence and underlying mechanisms.Food bioscience · 2021Review
- Combination of vegetable soup and glucan demonstrates synergistic effects on macrophage-mediated immune responses.Food science and biotechnology · 2021Article
- In Vivo Evaluation of Immune-Enhancing Activity of Red Gamju Fermented by ProbioticFoods (Basel, Switzerland) · 2021Article
- Continuous Exposure to Non-Soluble β-Glucans Induces Trained Immunity in M-CSF-Differentiated Macrophages.Frontiers in immunology · 2021Article
- An Artificial Intelligence Characterised Functional Ingredient, Derived from Rice, Inhibits TNF-α and Significantly Improves Physical Strength in an Inflammaging Population.Foods (Basel, Switzerland) · 2020Article
- Analysis of phenolic compounds and immunomodulatory activity of areca nut extract from Aceh, Indonesia, againstVeterinary world · 2020Article
- Cow's Milk Allergy: Immunomodulation by Dietary Intervention.Nutrients · 2019Review
- Beta Glucan: Supplement or Drug? From Laboratory to Clinical Trials.Molecules (Basel, Switzerland) · 2019Review
- Biomarkers in Food Allergy.Current allergy and asthma reports · 2018Review
- The Effect of Tomatine on Gene Expression and Cell Monolayer Integrity in Caco-2.Molecules (Basel, Switzerland) · 2018Article
- Effect of Feeding Soy Milk Fermented by Probiotic Bacteria on Some Blood Criteria and Weight of Experimental Animals.Probiotics and antimicrobial proteins · 2017Article
- Effects of Soluble Corn Fiber Alone or in Synbiotic Combination withFrontiers in immunology · 2017Article
- IM-133N - A Useful Herbal Combination for Eradicating Disease-triggering Pathogens in Mice via Immunotherapeutic Mechanisms.Journal of pharmacopuncture · 2016Article
- Orally administered β-glucan attenuates the Th2 response in a model of airway hypersensitivity.SpringerPlus · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The importance of a properly functioning and well-balanced immune system for maintaining health has become strikingly evident over the past decades. Roughly since World War II, there has been an apparent decrease in the prevalence of "traditional" infectious diseases, with a concomitant increase in immune-related disorders, such as allergies. Causally, a relationship with changes in life-style-related factors such as the increasing use of hygienic practices seems likely. Diet and nutrition can affect the functioning of various immune parameters. This concept can be utilised in attempts to prevent or mitigate allergic reactions via the development of targeted food products or ingredients. This review describes recent findings with respect to food products and ingredients that show potential in this respect, with special emphasis on pro- and prebiotics, beta-glucans and fungal immunomodulatory proteins. What all of these approaches have in common is that they appear to strengthen Th1-mediated immunity, thus possibly restoring defective immune maturation due to overly hygienic living conditions: a little bit of dirt does not seem bad!
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.