ReviewDer Orthopade2009
[Applications of molecular pathology in the diagnosis of joint infections].
Review in Der Orthopade, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 32 citations in OpenAlex.
- RNA-Seq Reveals the mRNAs, miRNAs, and lncRNAs Expression Profile of Knee Joint Synovial Tissue in Osteoarthritis Patients.Journal of clinical medicine · 2023Article
- [Histopathological classification principles of rheumatic joint diseases : Contribution of pathology to the diagnosis].Der Orthopade · 2018Review
- Expression of miR-146a, miR-155, and miR-223 in formalin-fixed paraffin-embedded synovial tissues of patients with rheumatoid arthritis and osteoarthritis.Virchows Archiv : an international journal of pathology · 2016Article
- [Histopathological diagnostic work-up of joint endoprosthesis-associated pathologies].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2016Review
- [Revision arthroplasty : Histopathological diagnostics in periprosthetic joint infections].Der Orthopade · 2015Article
- Investigation of neutrophilic peptides in periprosthetic tissue by matrix-assisted laser desorption ionisation time-of-flight imaging mass spectrometry.International orthopaedics · 2015Article
- [Molecular pathological diagnostics of infections in orthopedic pathology].Der Pathologe · 2014Review
- Histopathological Osteomyelitis Evaluation Score (HOES) - an innovative approach to histopathological diagnostics and scoring of osteomyelitis.GMS Interdisciplinary plastic and reconstructive surgery DGPW · 2014Article
- [Histopathology and microbiology of joint infections: extension of diagnostic safety in patients with chronic polyarthritis].Zeitschrift fur Rheumatologie · 2013Article
- [Histopathological differential diagnostics in context of joint implant allergic reactions].Der Orthopade · 2013Article
- [Indications for tissue biopsy. Diagnostic histopathology in rheumatological diseases].Zeitschrift fur Rheumatologie · 2012Article
- [Joint infections. Known facts and new trends].Der Unfallchirurg · 2012Article
- [Bone infections].Der Unfallchirurg · 2012Review
- Will polymerase chain reaction (PCR)-based diagnostics improve outcome in septic patients? A clinical view.Intensive care medicine · 2011Review
- [Infectious bone diseases].Der Pathologe · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The diagnosis of infections in patients with arthritis and/or joint prostheses requires interdisciplinary cooperation and the use of up-to-date methods. Massive bacterial infection can be identified by bacterial culture, and minimal infection can be detected by molecular pathological methods. These processes include specific enrichment of bacterial and fungal DNA, amplification, and identification of the DNA by gel electrophoresis, sequencing techniques, and chip technologies.Anamnesis (enteral or urogenital infection), the clinical picture (oligoarthritis), and further parameters (e.g., HLA B27 status) are important for the diagnosis of reactive arthritis. In many cases of reactive arthritis, molecular methods allow detection of bacterial DNA or RNA in synovial fluid or tissue. Molecular pathological methods allow the fast and reliable differential diagnosis of granulomatous synovialitis without prior cultivation of bacteria or fungi. The development of new molecular pathological methods for detecting bacterial and fungal nucleic acids will increase diagnostic accuracy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.