ArticleEvolutionary bioinformatics online2007
Genome halving with an outgroup.
Article in Evolutionary bioinformatics online, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed.
- IAGS: Inferring Ancestor Genome Structure under a Wide Range of Evolutionary Scenarios.Molecular biology and evolution · 2022Article
- Comparative genomics meets topology: a novel view on genome median and halving problems.BMC bioinformatics · 2016Article
- Endo-(1,4)-β-glucanase gene families in the grasses: temporal and spatial co-transcription of orthologous genes.BMC plant biology · 2012Article
- Fractionation, rearrangement and subgenome dominance.Bioinformatics (Oxford, England) · 2012Article
- Genome dedoubling by DCJ and reversal.BMC bioinformatics · 2011Article
- Genome rearrangements with duplications.BMC bioinformatics · 2010Article
- Multichromosomal median and halving problems under different genomic distances.BMC bioinformatics · 2009Article
- DUPCAR: reconstructing contiguous ancestral regions with duplications.Journal of computational biology : a journal of computational molecular cell biology · 2008Article
- Guided genome halving: hardness, heuristics and the history of the Hemiascomycetes.Bioinformatics (Oxford, England) · 2008Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Some genomes are known to have incurred a genome doubling (tetraploidization) event in their evolutionary history, and this is reflected today in patterns of duplicated segments scattered throughout their chromosomes. These duplications may be used as data to "halve" the genome, i.e. to reconstruct the an cestral genome at the moment of tetraploidization, but the solution is often highly non-unique. To resolve this problem, we adapt the genome halving algorithm of El-Mabrouk and Sankoff to take account of an external reference genome. We apply this to reconstruct the tetraploid ancestor of maize, using either rice or sorghum as the reference.
Indexed as
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19455223PMC2674651What OpenQuestion holds
Registered trials
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