Evidence map›Paper›PMID 19454622›Full record

Trial reportNeurorehabilitation and neural repair2009

Progressive shoulder abduction loading is a crucial element of arm rehabilitation in chronic stroke.

Michael D Ellis, Theresa Sukal-Moulton, Julius P A Dewald

2 registry-linked trialsOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Neurorehabilitation and neural repair, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 76 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed, 3 pooled it
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01548781 nacompletednot on this mapstarted 2012, after this paper: background citation

The Effect of Resistance to Participant-Supported Reaching on Workspace of the Hand in Severe Chronic Stroke

TypeinterventionalSponsorNorthwestern UniversityRan2012 to 2015Enrolled38ConditionsStrokeArmsImpairment-based robotic intervention for reaching function
NCT04118998 naactive not recruitingnot on this mapstarted 2021, after this paper: background citation

Progressive Abduction Loading Therapy: A Phase IIb Stroke Rehabilitation Trial With Longitudinal Tracking

TypeinterventionalSponsorNorthwestern UniversityRan2021 to 2027Enrolled86ConditionsStroke, AcuteArmsAbduction Loading, Supported Reaching
3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 3 syntheses or guidelines pooled it, 157 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Trial
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  8. Variations in neuromuscular electrical stimulation's ability to increase reach and hand opening during voluntary effort after stroke.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2012
    Trial
  9. Article
  10. Review
  11. Article
  12. Article
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  16. Human-in-the-Loop Myoelectric Pattern Recognition Control of an Arm-Support Robot to Improve Reaching in Stroke Survivors.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2025
    Article
  17. Beta-Band Cortico-Muscular Phase Coherence in Hemiparetic Stroke.Biomedical signal processing and control · 2024
    Article
  18. Article
  19. Article
  20. Article

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Michael D EllisDepartment of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, Illinois. m-ellis@northwestern.edu
Theresa Sukal-Moulton
Julius P A Dewald
Northwestern University · US

Funding

EFFECT OF NEURAL CONSTRAINTS ON MOVEMENT IN STROKER01HD039343 · NICHD · REHABILITATION INSTITUTE OF CHICAGO · PI JULIUS P DEWALD, JUN YAO · 2000 to 2026
$6.0M
NICHD NIH HHS L30 HD053903NICHD NIH HHS R01 HD039343
6 · The paper itself

Abstract

backgroundTotal reaching range of motion (work area) diminishes as a function of shoulder abduction loading in the paretic arm in individuals with chronic hemiparetic stroke. This occurs when reaching outward against gravity or during transport of an object.

objectivesThis study implements 2 closely related impairment-based interventions to identify the effect of a subcomponent of reaching exercise thought to be a crucial element in arm rehabilitation.

methodsA total of 14 individuals with chronic moderate to severe hemiparesis participated in the participant-blinded, randomized controlled study. The experimental group progressively trained for 8 weeks to actively support the weight of the arm, up to and beyond, while reaching to various outward targets. The control group practiced the same reaching tasks with matched frequency and duration with the weight of the arm supported. Work area and isometric strength were measured before and after the intervention.

resultsChange scores for work area at 9 loads were calculated for each group. Change scores were significantly larger for the experimental group indicating a larger increase in work area, especially shoulder abduction loads equivalent to those experienced during object transport. Changes in strength were not found within or between groups.

conclusionsProgressive shoulder abduction loading can be utilized to ameliorate reaching range of motion against gravity. Future work should investigate the dosage response of this intervention, as well as test whether shoulder abduction loading can augment other therapeutic techniques such as goal-directed functional task practice and behavioral shaping to enhance real-world arm function.

Indexed as

Stroke RehabilitationAgedArmChronic DiseaseFemaleHumansIsometric ContractionMaleMiddle AgedParesisPhysical Therapy ModalitiesRange of Motion, ArticularRoboticsShoulder JointStrokeWeight-Bearing

Identifiers

PMID19454622
PMCPMC2833097
OpenAlexW2106666697

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.