ReviewJournal of the Royal Society, Interface2009
Synthetic biology and biomass conversion: a match made in heaven?
Review in Journal of the Royal Society, Interface, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Real-World Synthetic Biology: Is It Founded on an Engineering Approach, and Should It Be?Life (Basel, Switzerland) · 2019Article
- Characterisation of novel biomass degradation enzymes from the genome of Cellulomonas fimi.Enzyme and microbial technology · 2018Article
- Enzymatic transformation of nonfood biomass to starch.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Engineering Escherichia coli for succinate production from hemicellulose via consolidated bioprocessing.Microbial cell factories · 2012Article
- Characterization of an inducible promoter in different DNA copy number conditions.BMC bioinformatics · 2012Article
- Heterologous expression of plant cell wall degrading enzymes for effective production of cellulosic biofuels.Journal of biomedicine & biotechnology · 2012Review
- Bottom-up engineering of biological systems through standard bricks: a modularity study on basic parts and devices.PloS one · 2012Article
- Metabolic engineering for production of biorenewable fuels and chemicals: contributions of synthetic biology.Journal of biomedicine & biotechnology · 2010Review
- Synthetic biology: history, challenges and prospects.Journal of the Royal Society, Interface · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To move our economy onto a sustainable basis, it is essential that we find a replacement for fossil carbon as a source of liquid fuels and chemical industry feedstocks. Lignocellulosic biomass, available in enormous quantities, is the only feasible replacement. Many micro-organisms are capable of rapid and efficient degradation of biomass, employing a battery of specialized enzymes, but do not produce useful products. Attempts to transfer biomass-degrading capability to industrially useful organisms by heterologous expression of one or a few biomass-degrading enzymes have met with limited success. It seems probable that an effective biomass-degradation system requires the synergistic action of a large number of enzymes, the individual and collective actions of which are poorly understood. By offering the ability to combine any number of transgenes in a modular, combinatorial way, synthetic biology offers a new approach to elucidating the synergistic action of combinations of biomass-degrading enzymes in vivo and may ultimately lead to a transferable biomass-degradation system. Also, synthetic biology offers the potential for assembly of novel product-formation pathways, as well as mechanisms for increased solvent tolerance. Thus, synthetic biology may finally lead to cheap and effective processes for conversion of biomass to useful products.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.