Evidence map›Paper›PMID 19453768›Full record

ArticleInsect molecular biology2009

Differential gene expression during compensatory sprouting of dendrites in the auditory system of the cricket Gryllus bimaculatus.

H W Horch, S S McCarthy, S L Johansen, J M Harris

Open access · bronzeAbstract read
In one paragraph

Article in Insect molecular biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. El grillo è buon cantore: for Franz Huber on the occasion of his 90th birthday.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2016
    Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

H W HorchBowdoin College, Department of Biology and Neuroscience, Brunswick, ME 04011, USA. hhorch@bowdoin.edu
S S McCarthy
S L Johansen
J M Harris
Bowdoin College · USBeth Israel Deaconess Medical Center · US

Funding

WNT SIGNALING IN THE DEVELOPING GASTROINTESTINAL TRACTP20RR016463 · NCRR · MOUNT DESERT ISLAND BIOLOGICAL LAB · PI WRAY, CHRISTOPHER C · 2001 to 2011
$41.0M
Development and regeneration of auditory interneuronsR15DC006889 · NIDCD · BOWDOIN COLLEGE · PI HORCH, HADLEY W · 2004 to 2004
$207k
NCRR NIH HHS P20 RR-016463NCRR NIH HHS P20 RR016463NIDCD NIH HHS 1 R15 DC006889-01NIDCD NIH HHS R15 DC006889
6 · The paper itself

Abstract

Neurones that lose their presynaptic partners because of injury usually retract or die. However, when the auditory interneurones of the cricket Gryllus bimaculatus are denervated, dendrites respond by growing across the midline and forming novel synapses with the opposite auditory afferents. Suppression subtractive hybridization was used to detect transcriptional changes 3 days after denervation. This is a stage at which we demonstrate robust compensatory dendritic sprouting. Whereas 49 unique candidates were down-regulated, no sufficiently up-regulated candidates were identified at this time point. Several candidates identified in this study are known to influence the translation and degradation of proteins in other systems. The potential role of these factors in the compensatory sprouting of cricket auditory interneurones in response to denervation is discussed.

Indexed as

Afferent PathwaysAnimalsDendritesGene Expression RegulationGryllidaeHearingInterneuronsSensory Deprivation

Identifiers

PMID19453768
PMCPMC3551613
OpenAlexW2152337333

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.