Evidence map›Paper›PMID 19453399›Full record

ReviewInfluenza and other respiratory viruses2008

Improving seasonal and pandemic influenza vaccines.

Melanie Saville, Grenville Marsh, Agnes Hoffenbach

Open access · bronzeAbstract readReview
In one paragraph

Review in Influenza and other respiratory viruses, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Cross-protection by co-immunization with influenza hemagglutinin DNA and inactivated virus vaccine using coated microneedles.Journal of controlled release : official journal of the Controlled Release Society · 2013
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Melanie SavilleResearch and Development Department, Sanofi Pasteur, 1541 Av. Marcel Mérieux, 69280 Marcy L Etoile, France. melanie.saville@sanofipasteur
Grenville Marsh
Agnes Hoffenbach
Sanofi (France) · FRInstitut Mérieux (France) · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Challenges facing seasonal and pandemic influenza vaccination include: increasing the immunogenicity of seasonal vaccines for the most vulnerable, increasing vaccination coverage against seasonal influenza, and developing vaccines against pandemic strains that are immunogenic with very low quantities of antigen to maximize the number of people who can be vaccinated with a finite production capacity. We review Sanofi Pasteur's epidemic and pandemic influenza research and development programmes with emphasis on two key projects: intradermal influenza vaccine for seasonal vaccination of both elderly and younger adults, and pandemic influenza vaccine.

Indexed as

Adjuvants, ImmunologicAdultAgedAged, 80 and overDisease OutbreaksHumansImmunizationInfluenza, HumanInfluenza VaccinesInjections, IntradermalMiddle AgedYoung AdultAdjuvants, ImmunologicInfluenza Vaccines

Identifiers

PMID19453399
PMCPMC4634120
OpenAlexW2031717634

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.