SynthesisSports medicine (Auckland, N.Z.)2009
The antidepressive effects of exercise: a meta-analysis of randomized trials.
Synthesis in Sports medicine (Auckland, N.Z.), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 197 papers, 27 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
197 citing papers in PubMed, 27 syntheses or guidelines pooled it, 535 citations in OpenAlex.
- Association Between Physical Activity, Heart Rate Variability and Major Depressive Disorders: An Umbrella Review.Sports medicine (Auckland, N.Z.) · 2026Pooled it
- Exercise interventions are most consistently supported for depressive disorders: an umbrella review of diagnosed depressive and anxiety disorders.Frontiers in psychiatry · 2026Pooled it
- Effects of Exercise on Depression and Anxiety in Lung Cancer Survivors: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Current oncology (Toronto, Ont.) · 2025Pooled it
- The effects of physical activity on the mental health of typically developing children and adolescents: a systematic review and meta-analysis.BMC public health · 2025Pooled it
- Effects of Exercise on Depression and Anxiety in Breast Cancer Survivors: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Cancer medicine · 2025Pooled it
- Effectiveness of exercise intervention on children and adolescents with depression: a systematic review and meta-analysis of randomized controlled trial.Frontiers in psychiatry · 2025Pooled it
- Meta-analysis of the effectiveness of exercise as an intervention for suicidal tendency in depressed patients.Frontiers in psychology · 2025Pooled it
- The effects of physical activity interventions on self-esteem during and after cancer treatment: a systematic review and meta-analysis.Scientific reports · 2024Pooled it
- The effects of exercise on antenatal depression: a systematic review and meta-analysis.Frontiers in psychiatry · 2024Pooled it
- The effect of physical exercise on depression among college students: a systematic review and meta-analysis.PeerJ · 2024Pooled it
- The Effects of Physical Activity on Positive Emotions in Children and Adolescents: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022Pooled it
- Pooled it
- Comparative efficacy of seven exercise interventions for symptoms of depression in college students: A network of meta-analysis.Medicine · 2020Pooled it
- Exercise interventions for the prevention of depression: a systematic review of meta-analyses.BMC public health · 2020Pooled it
- Depression in Somatic Disorders: Is There a Beneficial Effect of Exercise?Frontiers in psychiatry · 2019Pooled it
- The 2017 Dutch Physical Activity Guidelines.The international journal of behavioral nutrition and physical activity · 2018Pooled it
- Challenges Establishing the Efficacy of Exercise as an Antidepressant Treatment: A Systematic Review and Meta-Analysis of Control Group Responses in Exercise Randomised Controlled Trials.Sports medicine (Auckland, N.Z.) · 2016Pooled it
- Depression Symptom Severity and Cardiorespiratory Fitness in Healthy and Depressed Adults: A Systematic Review and Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2016Pooled it
- The efficacy of physiotherapy for the prevention and treatment of prenatal symptoms: a systematic review.International urogynecology journal · 2015Pooled it
- Quantifying the placebo effect in psychological outcomes of exercise training: a meta-analysis of randomized trials.Sports medicine (Auckland, N.Z.) · 2015Pooled it
137 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several meta-analyses examining the effects of exercise on depression have been criticized for including studies of poor methodological integrity. More recent meta-analyses addressed the most common criticism by including only randomized control trials; however, these analyses suffer from incomplete literature searches and lack of moderating variable analyses. Using a more extensive search procedure, the current meta-analysis examines the effects of exercise on depressive symptoms in 58 randomized trials (n = 2982). An overall effect size of -0.80 indicates participants in the exercise treatment had significantly lower depression scores than those receiving the control treatment. This frac34; SD advantage represents level 1, Grade A evidence for the effects of exercise upon depression. Analysis of moderating variables examined the influence of population characteristics, exercise characteristics and methodological characteristics. Examination of clinical significance in 16 trials with clinically depressed patients found 9 of 16 exercise treatment groups were classified as 'recovered' at post-treatment, with another three groups classified as 'improved'. Analysis showed dropout rates for the exercise treatment were similar to those found in psychotherapeutic and drug interventions.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.