ReviewThe Journal of cell biology2009
Revisiting the role of heterochromatin protein 1 in DNA repair.
Review in The Journal of cell biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 26 citations in OpenAlex.
- HP1β recruits RING1A to ubiquitinate histone H2A for BRCA1-mediated resection of double-stand breaks.iScience · 2026Article
- Histone post-translational modification and the DNA damage response.Genes & diseases · 2023Review
- CBX3 Promotes Gastric Cancer Progression and Affects Factors Related to Immunotherapeutic Responses.Cancer management and research · 2020Article
- Article
- LRIF1 interacts with HP1α to coordinate accurate chromosome segregation during mitosis.Journal of molecular cell biology · 2018Article
- Function of heterochromatin protein 1 during DNA repair.Protoplasma · 2017Review
- Article
- The spatiotemporal dynamics of chromatin protein HP1α is essential for accurate chromosome segregation during cell division.The Journal of biological chemistry · 2014Article
- HP1 promotes tumor suppressor BRCA1 functions during the DNA damage response.Nucleic acids research · 2013Article
- Article
- Heterochromatin influences the secondary metabolite profile in the plant pathogen Fusarium graminearum.Fungal genetics and biology : FG & B · 2012Article
- DNA damage response.Cold Spring Harbor perspectives in biology · 2011Review
- Requirement of ATM-dependent pathway for the repair of a subset of DNA double strand breaks created by restriction endonucleases.Genome integrity · 2010Article
- HP1: heterochromatin binding proteins working the genome.Epigenetics · 2010Review
- Tip60: connecting chromatin to DNA damage signaling.Cell cycle (Georgetown, Tex.) · 2010Review
Corrections and comments
- Comment on
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heterochromatin protein 1 (HP1) is a conserved factor critical for heterochromatin organization and gene silencing. It is recruited to chromatin by its direct interaction with H3K9me (methylated lysine 9 residue of histone H3), an epigenetic mark for silenced chromatin. Now, Luijsterburg et al. (Luijsterburg, M.S., C. Dinant, H. Lans, J. Stap, E. Wiernasz, S. Lagerwerf, D.O. Warmerdam, M. Lindh, M.C. Brink, J.W. Dobrucki, et al. 2009. J. Cell Biol. 185:577-586) reveal a new H3K9me-independent role for HP1 in the DNA damage response, which is distinct from the one recently reported by Ayoub et al. (Ayoub, N., A.D. Jeyasekharan, J.A. Bernal, and A.R. Venkitaraman. 2008. Nature. 453:682-686).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.