ReviewVirology journal2009
Replication of porcine circoviruses.
Review in Virology journal, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 82 citations in OpenAlex.
- Structures of nucleotide-bound Redondovirus Rep protein link conformation and function.PLoS pathogens · 2026Article
- The C1QTNF6-MX2 Antiviral Axis Inhibits Porcine Circovirus Type 2 Replication in Porcine Macrophages.Veterinary sciences · 2025Article
- Potential New Avian Species as Carriers of Diverse Circoviruses.Pathogens (Basel, Switzerland) · 2025Article
- Nicking Activity of M13 Bacteriophage Protein 2.International journal of molecular sciences · 2025Article
- Canine circovirus: emergence, adaptation, and challenges for animal and public health.Frontiers in veterinary science · 2025Review
- Review
- Revisiting Porcine Circovirus Infection: Recent Insights and Its Significance in the Piggery Sector.Vaccines · 2023Review
- Canine circovirus: An emerging or an endemic undiagnosed enteritis virus?Frontiers in veterinary science · 2023Review
- Diversity of CRESS DNA Viruses in Squamates Recapitulates Hosts Dietary and Environmental Sources of Exposure.Microbiology spectrum · 2022Article
- Whole-Genome Sequence of a Porcine Circovirus Type 2 Strain Detected in Assam, India.Microbiology resource announcements · 2022Article
- Computational based design and tracking of synthetic variants of Porcine circovirus reveal relations between silent genomic information and viral fitness.Scientific reports · 2021Article
- Porcine Circovirus Type 2 Pathogenicity Alters Host's Central Tolerance for Propagation.Pathogens (Basel, Switzerland) · 2020Article
- Virus-Host Coevolution with a Focus on Animal and Human DNA Viruses.Journal of molecular evolution · 2020Review
- Apoptosis Triggered by ORF3 Proteins of theFrontiers in cellular and infection microbiology · 2020Review
- Novel single-stranded, circular DNA virus identified in cats in Japan.Archives of virology · 2018Article
- Crystal Structure of the Dimerized N Terminus of Porcine Circovirus Type 2 Replicase Protein Reveals a Novel Antiviral Interface.Journal of virology · 2018Article
- The occurrence of porcine circovirus 3 without clinical infection signs in Shandong Province.Transboundary and emerging diseases · 2017Article
- Interactions of porcine circovirus 2 with its hosts.Virus genes · 2016Review
- A Helitron transposon reconstructed from bats reveals a novel mechanism of genome shuffling in eukaryotes.Nature communications · 2016Article
- Complete genome sequence of porcine circovirus strain 102 with a novel mutation, isolated from hunan province, china.Genome announcements · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Porcine circoviruses are circular single-stranded DNA viruses that infect swine and wild boars. Two species of porcine circoviruses exist. Porcine circovirus type 1 is non pathogenic contrary to porcine circovirus type 2 which is associated with the disease known as Post-weaning Multisystemic Wasting Syndrome. Porcine circovirus DNA has been shown to replicate by a rolling circle mechanism. Other studies have revealed similar mechanisms of rolling-circle replication in plasmids and single-stranded viruses such as Geminivirus. Three elements are important in rolling-circle replication: i) a gene encoding initiator protein, ii) a double strand origin, and iii) a single strand origin. However, differences exist between viruses and plasmids and between viruses. Porcine circovirus replication probably involves a "melting pot" rather than "cruciform" rolling-circle mechanism.This review provides a summary of current knowledge of replication in porcine circoviruses as models of the Circovirus genus. Based on various studies, the factors affecting replication are defined and the mechanisms involved in the different phases of replication are described or proposed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.