Evidence map›Paper›PMID 19450141›Full record

Trial reportMetabolic syndrome and related disorders2009

Prevalence of the metabolic syndrome among obese adolescents enrolled in a multidisciplinary weight management program: clinical correlates and response to treatment.

Edmond P Wickham, Marilyn Stern, Ronald K Evans, Daphne L Bryan, William B Moskowitz, John N Clore, Joseph H Laver

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in Metabolic syndrome and related disorders, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00167830 (Understanding The Barriers in Treatment of Obesity in Adolescents 11-18 in Central Virginia), which is not on this map. Cited by 33 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00167830 phase1 / phase2completednot on this map

Understanding The Barriers in Treatment of Obesity in Adolescents 11-18 in Central Virginia

TypeinterventionalSponsorVirginia Commonwealth UniversityRan2003 to 2013Enrolled292ConditionsObesityArmsMotivational Interviewing, Strength and Cardiovascular Conditioning, Food selection and portion control
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  19. Impact of Recreational Sports Activities on Metabolic Syndrome Components in Adolescents.International journal of environmental research and public health · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Edmond P WickhamDepartment of Pediatrics, Virginia Commonwealth University, Richmond, Virginia 23298-0111, USA. ewickham@mcvh-vcu.edu
Marilyn Stern
Ronald K Evans
Daphne L Bryan
William B Moskowitz
John N Clore
Joseph H Laver

Funding

X-LINKED HYPOPHOSPHATEMIAM01RR000065 · NCRR · VIRGINIA COMMONWEALTH UNIVERSITY · PI SANYAL, ARUN J · 1985 to 2010
$24.8M
Center for Clinical and Translational ResearchUL1TR000058 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI MOELLER, FREDERICK GERARD · 2012 to 2015
$12.5M
NCATS NIH HHS UL1 TR000058NCRR NIH HHS M01 RR00065
6 · The paper itself

Abstract

objectiveThe aim of this study was to determine the prevalence of the metabolic syndrome at baseline and after 6 months of lifestyle modification among obese adolescents referred to a multidisciplinary weight management program.

methodsA total of 165 obese adolescents were evaluated at baseline, and measurements were repeated in 57 subjects who completed 6 months of the program. Metabolic syndrome was defined as having three or more of the following: a body mass index (BMI) >97(th) percentile, hypertension, low high-density lipoprotein cholesterol (HDL-C), hypertriglyceridemia, and impaired fasting glucose (IFG).

resultsThe prevalence of a BMI >97(th) percentile, hypertension, hypertriglyceridemia, low HDL-C, and IFG was 92.7, 54.5, 29.1, 26.7, and 2.4%, respectively. The prevalence of the metabolic syndrome at baseline was 30.3%. After 6 months of lifestyle modification, BMI z scores, percent body fat, total cholesterol, and low-density lipoprotein cholesterol (LDL-C) decreased significantly from baseline; however, there was no significant change in the number of subjects demonstrating >or=three criteria of the metabolic syndrome.

conclusionsApproximately one third of the study subjects met the criteria of the metabolic syndrome, emphasizing the growing concern for the future development of premature cardiovascular disease in this high-risk population. Our data suggest that new strategies for lifestyle modification may be needed to improve cardiovascular risk factors significantly among adolescents with obesity.

Indexed as

AdolescentBehavior TherapyBlood GlucoseBody Mass IndexCardiovascular DiseasesChildCombined Modality TherapyDiet TherapyExercise TherapyFemaleHealth PromotionHumansLipoproteins, HDLMaleMetabolic SyndromeObesityBlood GlucoseLipoproteins, HDLTriglycerides

Identifiers

PMID19450141
PMCPMC3135889

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.