ReviewAnnual review of microbiology2009
Lipid signaling in pathogenic fungi.
Review in Annual review of microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 46 citations in OpenAlex.
- Mechanisms and Advances in Plant Lipid Regulatory Responses Under Biotic and Abiotic Stress.Genes · 2026Review
- Fatty acid synthesis: A critical factor determining mycelial growth rate inFood chemistry. Molecular sciences · 2025Article
- Fatty acids in filamentous pathogenic fungi: Multidimensional regulation and pathogenic mechanisms.Virulence · 2025Review
- Diacylglycerol metabolism and homeostasis in fungal physiology.FEMS yeast research · 2024Review
- The sensor histidine kinase (SLN1) and acetyl-CoA carboxylase (ACC1) coordinately regulate the response ofApplied and environmental microbiology · 2023Article
- Metabolome and Transcriptome Combinatory Profiling Reveals Fluconazole Resistance Mechanisms ofMicroorganisms · 2023Article
- The biological functions of sphingolipids in plant pathogenic fungi.PLoS pathogens · 2023Review
- Solid-state NMR molecular snapshots ofProceedings of the National Academy of Sciences of the United States of America · 2023Article
- Article
- Functional characterization of the AGL1 aegerolysin in the mycoparasitic fungus Trichoderma atroviride reveals a role in conidiation and antagonism.Molecular genetics and genomics : MGG · 2021Article
- A comprehensive insight into the lipid composition of Myxococcus xanthus by UPLC-ESI-MS.Journal of lipid research · 2014Article
- The capacity ofFungal biology and biotechnology · 2014Article
- An assessment of growth media enrichment on lipid metabolome and the concurrent phenotypic properties of Candida albicans.PloS one · 2014Article
- Article
- Spatial reorganization of Saccharomyces cerevisiae enolase to alter carbon metabolism under hypoxia.Eukaryotic cell · 2013Article
- Detection of antibody against fungal glucosylceramide in immunocompromised patients: a potential new diagnostic approach for cryptococcosis.Mycopathologia · 2012Article
- Modulation of morphogenesis in Candida albicans by various small molecules.Eukaryotic cell · 2011Review
- Genome-wide expression profiling of the response to short-term exposure to fluconazole in Cryptococcus neoformans serotype A.BMC microbiology · 2011Article
- Expanding fungal pathogenesis: Cryptococcus breaks out of the opportunistic box.Nature reviews. Microbiology · 2011Review
- Asymmetric synthesis of D-ribo-phytosphingosine from 1-tetradecyne and (4-methoxyphenoxy)acetaldehyde.The Journal of organic chemistry · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Lipid signaling in pathogenic fungi has been studied to determine the role of these pathways in fungal biology and human infections. Owing to their unique nature, they may represent targets for future antifungal treatments. Farnesol signaling was characterized as a quorum-sensing molecule, with exposure inhibiting filamentation. Research has shown involvement in both the Ras1-adenylate cyclase and MAP kinase pathways. In species of Aspergillus, farnesol exposure induces apoptosis-like changes and alterations in ergosterol synthesis. Eicosanoid production has been characterized in several pathogenic fungi, utilizing host lipids in some cases. The role in virulence is not known yet, but it may involve modulation of host lipids. Sphingolipid signaling pathways seem to center around the production of diacylglycerol in the formation of inositol phosphorylceramide. Diacylglycerol activates both melanin production through laccase and transcription of antiphagocytic protein, both of which are involved in virulence.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.