ArticleJournal of psychiatry & neuroscience : JPN2009
Influence of androgen receptor repeat polymorphisms on personality traits in men.
Article in Journal of psychiatry & neuroscience : JPN, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 74 citations in OpenAlex.
- Interplay of polymorphisms in sex hormone receptors and facial sexual differentiation in shaping prosocial behavior.Scientific reports · 2025Article
- Influence of gonadal steroids on cortical surface area in infancy.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- The evolution and polymorphism of mono-amino acid repeats in androgen receptor and their regulatory role in health and disease.Frontiers in medicine · 2022Review
- The influence of microsatellite polymorphisms in sex steroid receptor genes ESR1, ESR2 and AR on sex differences in brain structure.NeuroImage · 2020Article
- The Relation Between Steroid Secretion Patterns and the Androgen Receptor Gene Polymorphism on Physical Health and Psychological Well-Being-Longitudinal Findings From the Men's Health 40+ Study.Frontiers in human neuroscience · 2020Article
- Polymorphisms in sex steroid receptors: From gene sequence to behavior.Frontiers in neuroendocrinology · 2017Review
- Microsatellite polymorphisms associated with human behavioural and psychological phenotypes including a gene-environment interaction.BMC medical genetics · 2017Article
- Androgen receptor CAG polymorphism and sporadic and early-onset prostate cancer among Mexican men.Journal of human genetics · 2016Article
- Androgen Receptor Gene Polymorphism, Aggression, and Reproduction in Tanzanian Foragers and Pastoralists.PloS one · 2015Article
- Article
- A preliminary case study of androgen receptor gene polymorphism association with impulsivity in women with alcoholism.Advances in genomics and genetics · 2014Article
- Androgen receptor gene mutation, rearrangement, polymorphism.Translational andrology and urology · 2013Article
- Androgen receptor polyglutamine repeat number: models of selection and disease susceptibility.Evolutionary applications · 2013Article
- Genetic determinants of aggression and impulsivity in humans.Journal of applied genetics · 2012Review
- Androgen receptor gene polymorphisms are associated with aggression in Japanese Akita Inu.Biology letters · 2011Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTestosterone has been attributed importance for various aspects of behaviour. The aim of our study was to investigate the potential influence of 2 functional polymorphisms in the amino terminal of the androgen receptor on personality traits in men.
methodsWe assessed and genotyped 141 men born in 1944 recruited from the general population. We used 2 different instruments: the Karolinska Scales of Personality and the Temperament and Character Inventory. For replication, we similarly assessed 63 men recruited from a forensic psychiatry study group.
resultsIn the population-recruited sample, the lengths of the androgen receptor repeats were associated with neuroticism, extraversion and self-transcendence. The association with extraversion was replicated in the independent sample. LIMITATIONS: Our 2 samples differed in size; sample 1 was of moderate size and sample 2 was small. In addition, the homogeneity of sample 1 probably enhanced our ability to detect significant associations between genotype and phenotype.
conclusionOur results suggest that the repeat polymorphisms in the androgen receptor gene may influence personality traits in men.
Indexed as
Identifiers
19448851PMC2674974W2152739258What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.