Evidence map›Paper›PMID 19446075›Full record

ReviewHormones and behavior2009

Sex differences in the brain: the relation between structure and function.

Geert J de Vries, Per Södersten

Abstract readReview
In one paragraph

Review in Hormones and behavior, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Sex differences in the neural circuitry of aggression.bioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Sex Differences in Human Brain Structure at Birth.Biology of sex differences · 2024
    Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Transwoman Elite Athletes: Their Extra Percentage Relative to Female Physiology.International journal of environmental research and public health · 2022
    Review
  20. Teaching About Sex and Gender in Neuroscience: More Than Meets the "XY".Journal of undergraduate neuroscience education : JUNE : a publication of FUN, Faculty for Undergraduate Neuroscience · 2022
    Article

21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Geert J de VriesDepartment of Psychology and Center for Neuroendocrine Studies, Tobin Hall, University of Massachusetts, Amherst, MA 01003 9333, USA. devries@cns.umass.edu
Per Södersten

Funding

The Neural Basis of Sexually Dimorphic Brain FunctionR01MH047538 · NIMH · UNIVERSITY OF MASSACHUSETTS AMHERST · PI DE VRIES, GEERT J. · 1991 to 2013
$3.2M
The Neural Basis of Sexually Dimorphic Brain FunctionK02MH001497 · NIMH · UNIVERSITY OF MASSACHUSETTS AMHERST · PI DE VRIES, GEERT J · 1998 to 2007
$930k
NIMH NIH HHS K02 MH001497NIMH NIH HHS MH047538NIMH NIH HHS R01 MH047538
6 · The paper itself

Abstract

In the fifty years since the organizational hypothesis was proposed, many sex differences have been found in behavior as well as structure of the brain that depend on the organizational effects of gonadal hormones early in development. Remarkably, in most cases we do not understand how the two are related. This paper makes the case that overstating the magnitude or constancy of sex differences in behavior and too narrowly interpreting the functional consequences of structural differences are significant roadblocks in resolving this issue.

Indexed as

AndrogensAnimalsBrainFemaleHumansIn Vitro TechniquesSex DifferentiationSexual BehaviorSexual Behavior, AnimalAndrogens

Identifiers

PMID19446075
PMCPMC3932614

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.