ArticleBMC public health2009
Can differences in medical drug compliance between European countries be explained by social factors: analyses based on data from the European Social Survey, round 2.
Article in BMC public health, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effect of Electronic Prescribing Compared to Paper-Based (Handwritten) Prescribing on Primary Medication Adherence in an Outpatient Setting: A Systematic Review.Applied clinical informatics · 2021Pooled it
- Medication Adherence During Adjunct Therapy With Statins and ACE Inhibitors in Adolescents With Type 1 Diabetes.Diabetes care · 2020Trial
- Quantifying income inequality in years of life lost to COVID-19: a prediction model approach using Dutch administrative data.International journal of epidemiology · 2024Article
- High burden of drug therapy in adult congenital heart disease: polypharmacy as marker of morbidity and mortality.European heart journal. Cardiovascular pharmacotherapy · 2019Article
- Determinants of Primary Nonadherence to Medications Prescribed by General Practitioners Among Adults in Hungary: Cross-Sectional Evaluation of Health Insurance Data.Frontiers in pharmacology · 2019Article
- Adherence to chronic medication in older populations: application of a common protocol among three European cohorts.Patient preference and adherence · 2018Article
- Patient adherence to subcutaneous IFN beta-1a injections using the RebiSmartPatient preference and adherence · 2017Article
- Cost-Effectiveness of Proton Pump Inhibitor Co-Therapy in Patients Taking Aspirin for Secondary Prevention of Ischemic Stroke.PharmacoEconomics · 2015Article
- Drug adherence in patients taking oral anticoagulation therapy.Clinical research in cardiology : official journal of the German Cardiac Society · 2014Review
- Adherence in adults with type 1 diabetes mellitus correlates with treatment satisfaction but not with adverse events.Patient preference and adherence · 2013Article
- Patient preferences for first-line oral treatment for mild-to-moderate ulcerative colitis: a discrete-choice experiment.The patient · 2012Article
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Authors and funding
4 authors.
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Abstract
backgroundNon-compliance with medication is a major health problem. Cultural differences may explain different compliance patterns. The size of the compliance burden and the impact of socio-demographic and socio-economic status within and across countries in Europe have, however, never been analysed in one survey. The aim of this study was to analyse 1) medical drug compliance in different European countries with respect to socio-demographic and socio-economic factors, and to examine 2) whether cross-national differences could be explained by these factors.
methodsA multi-country interview survey European Social Survey, Round 2 was conducted in 2004/05 comprising questions about compliance with last prescribed drug. Non-compliance was classified as primary and secondary, depending whether the drug was purchased or not. Statistical weighting allowed for adjustment for national differences in sample mechanisms. A multiple imputation strategy was used to compensate for missing values. The analytical approach included multivariate and multilevel analyses.
resultsThe survey comprised 45,678 participants. Response rate was 62.5% (range 43.6-79.1%). Reported compliance was generally high (82%) but the pattern of non-compliance showed large variation between countries. Some 3.2% did not purchase the most recently prescribed medicine, and 13.6% did not take the medicine as prescribed. Multiple regression analyses showed that each variable had very different and in some cases opposite impact on compliance within countries. The multilevel analysis showed that the variation between countries did not change significantly when adjusted for increasing numbers of covariates.
conclusionReported compliance was generally high but showed wide variation between countries. Cross-national differences could, however, not be explained by the socio-demographic and socio-economic variables measured.
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