ArticleNeurocritical care2009
Pitfalls in the diagnosis of brain death.
Article in Neurocritical care, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 79 citations in OpenAlex.
- Guidelines for the assessment and acceptance of potential brain-dead organ donors.Revista Brasileira de terapia intensiva · 2016Guideline
- Computed tomography angiography in the diagnosis of brain death: a systematic review and meta-analysis.Neurocritical care · 2014Pooled it
- Computed tomography (CT) angiography for confirmation of the clinical diagnosis of brain death.The Cochrane database of systematic reviews · 2014Pooled it
- A structured analysis of the concept of brain death.Theoretical medicine and bioethics · 2026Article
- Role of Clinical and Multimodality Neuroimaging in the Evaluation of Brain Death/Death by Neurologic Criteria and Recent Highlights from 2023 Updated Guidelines.Diagnostics (Basel, Switzerland) · 2024Review
- Suitability of electroencephalography in brain death determination: a monocentric, 10-year retrospective, observational investigation of 428 cases.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023Observational
- Deceased Organ Transplantation in Bangladesh: The Dynamics of Bioethics, Religion and Culture.HEC forum : an interdisciplinary journal on hospitals' ethical and legal issues · 2022Article
- Eye-opening in brain death: A case report and review of the literature.Clinical neurophysiology practice · 2022Article
- [Irreversible brain death-Part 2. Spinalization phenomena].Der Nervenarzt · 2021Review
- South African guidelines on the determination of death.The Southern African journal of critical care : the official journal of the Critical Care Society · 2021Article
- [Irreversible loss of brain function-Part 1: pitfalls in clinical diagnosis].Der Nervenarzt · 2020Article
- Organ Donation and Declaration of Death: Combined Neurologic and Cardiopulmonary Standards.The Linacre quarterly · 2019Article
- Finger Flexion to Noxious Stimulation in a Brain-dead Patient: A Case Report and Review of Literature.Cureus · 2018Article
- Prolonged duration of apnea test during brain death examination in a case of intraparenchymal hemorrhage.SAGE open medical case reports · 2017Article
- Revised CT angiography venous score with consideration of infratentorial circulation value for diagnosing brain death.Annals of intensive care · 2016Article
- Renaissance of criticism on the concept of brain death--the role of legal medicine in the context of the interdisciplinary discussion.International journal of legal medicine · 2016Article
- The standardization debate: A conflation trap in critical care electroencephalography.Seizure · 2015Review
- Controversies in defining and determining death in critical care.Nature reviews. Neurology · 2013Review
- Technical aids in the diagnosis of brain death: a comparison of SEP, AEP, EEG, TCD and CT angiography.Deutsches Arzteblatt international · 2012Article
- Mass media campaigns and organ donation: managing conflicting messages and interests.Medicine, health care, and philosophy · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since the establishment of the concept of declaring death by brain criteria, a large extent of variability in the determination of brain death has been reported. There are no standardized practical guidelines, and major differences exist in the requirements for the declaration of brain death throughout the USA and internationally. The American Academy of Neurology published evidence-based practice parameters for the determination of brain death in adults in 1995, requiring the irreversible absence of clinical brain function with the cardinal features of coma, absent brainstem reflexes, and apnea, as well as the exclusion of reversible confounders. Ancillary tests are recommended in cases of uncertainty of the clinical diagnosis. Every step in the determination of brain death bears potential pitfalls which can lead to errors in the diagnosis of brain death. These pitfalls are presented here, and possible solutions identified. Suggestions are made for improvement in the standardization of the declaration of brain death.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.