Trial reportSurgical endoscopy2009
Randomized controlled trial on sterile fluid collections management in acute pancreatitis: should they be removed?
Trial report in Surgical endoscopy, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02648815 (Management of Moderate and Severe Forms of Acute Pancreatitis), which is not on this map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Management of Moderate and Severe Forms of Acute Pancreatitis
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Endoscopic transluminal necrosectomy in necrotising pancreatitis: a systematic review.Surgical endoscopy · 2014Pooled it
- Endoscopic transmural necrosectomy for walled-off pancreatic necrosis: a systematic review and meta-analysis.Canadian journal of gastroenterology & hepatology · 2014Pooled it
- Trial
- Research on the classification of pancreatic pseudocysts based on individualized treatment protocols.BMC surgery · 2025Article
- Early short-term abdominal paracentesis drainage in moderately severe and severe acute pancreatitis with pelvic ascites.BMC surgery · 2023Article
- Current trends in acute pancreatitis: Diagnostic and therapeutic challenges.World journal of gastroenterology · 2023Review
- Clinical Characteristics of Acute Pancreatitis Patients with Multidrug-Resistant Bacterial Infection.Infection and drug resistance · 2022Article
- Catheter-Related Complications of Percutaneous Drainage in Step-up Approach for Management of Pancreatic Necrosis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2020Article
- Infectious Complications in Severe Acute Pancreatitis: Pathogens, Drug Resistance, and Status of Nosocomial Infection in a University-Affiliated Teaching Hospital.Digestive diseases and sciences · 2020Article
- Early predictors of hyperlipidemic acute pancreatitis.Experimental and therapeutic medicine · 2018Article
- Early ultrasound-guided percutaneous catheter drainage in the treatment of severe acute pancreatitis with acute fluid accumulation.Experimental and therapeutic medicine · 2018Article
- A percutaneous drainage protocol for severe and moderately severe acute pancreatitis.Surgical endoscopy · 2015Article
- Minimally invasive treatment of pancreatic pseudocysts.World journal of gastroenterology · 2015Review
- Retroperitoneal abscess and acute acalculous cholecystitis after iatrogenic colon injury: report of a case.International journal of clinical and experimental medicine · 2015Article
- Is necrosectomy obsolete for infected necrotizing pancreatitis? Is a paradigm shift needed?World journal of gastroenterology · 2014Review
- Treatment of severe acute pancreatitis and its complications.World journal of gastroenterology · 2014Review
- Position paper: timely interventions in severe acute pancreatitis are crucial for survival.World journal of emergency surgery : WJES · 2014Article
- Comments on the article about the treatment of infected pancreatic necrosis.Surgical endoscopy · 2013Article
- Surgical treatment of acute pancreatitis.Langenbeck's archives of surgery · 2013Review
- Is irrigation necessary during endoscopic necrosectomy of pancreatic necroses?Surgical endoscopy · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate if percutaneous drainage of sterile fluid collections recurring after initial aspiration in acute pancreatitis yields better results than their conservative management.
methodsFifty-eight patients with fluid collections in acute pancreatitis were followed up prospectively. Forty of them with sterile fluid collections that recurred after initial aspiration were randomly assigned to two groups of 20 in each. One group was initially treated with conservative management and the other group with prolonged catheter drainage. Patients with unsuccessful initial treatment were converted to more aggressive procedure. Outcome measure was conversion rate to more aggressive procedure.
resultsConversion to more aggressive procedure was done in 11 and 3 patients treated conservatively and with catheter drainage, respectively (p = 0.02). Four and 11 patients had bacterial colonization of their fluid collections in conservative management and drainage group, respectively (p = 0.048). Conservative treatment was successful in all six patients with sterile liquid collections < 30 ml. However, this treatment was unsuccessful in all seven patients with multiloculated and liquid collections >100 ml.
conclusionsProlonged catheter drainage is more efficient for management of recurrent sterile fluid collections in acute pancreatitis than is conservative treatment. Conservative treatment is successful for patients with small fluid collections.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.