ArticleJournal of experimental botany2009
Stilbene synthase gene transfer caused alterations in the phenylpropanoid metabolism of transgenic strawberry (Fragaria x ananassa).
Article in Journal of experimental botany, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 65 citations in OpenAlex.
- Enhanced scab resistance in apple conferred by Rvi6 and polyploidy is linked with distinct shifts in the phenolics profile.Scientific reports · 2025Article
- Resveratrol synthase homologs participate in infection ofFrontiers in microbiology · 2025Article
- Preliminary Study to Assess the Impact of Dietary Rutin on Growth, Antioxidant Capacity, and Intestinal Health of Yellow Catfish,Animals : an open access journal from MDPI · 2023Article
- Spiro-Flavonoids in Nature: A Critical Review of Structural Diversity and Bioactivity.Molecules (Basel, Switzerland) · 2023Review
- Article
- Identification of a strawberry NPR-like gene involved in negative regulation of the salicylic acid-mediated defense pathway.PloS one · 2018Article
- RNAi-mediated endogene silencing in strawberry fruit: detection of primary and secondary siRNAs by deep sequencing.Plant biotechnology journal · 2017Article
- System-Level and Granger Network Analysis of Integrated Proteomic and Metabolomic Dynamics Identifies Key Points of Grape Berry Development at the Interface of Primary and Secondary Metabolism.Frontiers in plant science · 2017Article
- Deep sequencing reveals transcriptome re-programming of Polygonum multiflorum thunb. roots to the elicitation with methyl jasmonate.Molecular genetics and genomics : MGG · 2016Article
- Article
- Genetic transformation of fruit trees: current status and remaining challenges.Transgenic research · 2012Review
- Resveratrol biosynthesis: plant metabolic engineering for nutritional improvement of food.Plant foods for human nutrition (Dordrecht, Netherlands) · 2012Review
- Overexpression of a resveratrol synthase gene (PcRS) from Polygonum cuspidatum in transgenic Arabidopsis causes the accumulation of trans-piceid with antifungal activity.Plant cell reports · 2011Article
- High-yield resveratrol production in engineered Escherichia coli.Applied and environmental microbiology · 2011Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The gene encoding stilbene synthase is frequently used to modify plant secondary metabolism with the aim of producing the self-defence phytoalexin resveratrol. In this study, strawberry (Fragaria x ananassa) was transformed with the NS-Vitis3 gene encoding stilbene synthase from frost grape (Vitis riparia) under the control of the cauliflower mosaic virus 35S and the floral filament-specific fil1 promoters. Changes in leaf metabolites were investigated with UPLC-qTOF-MS (ultra performance liquid chromatography-quadrupole time of flight mass spectrometry) profiling, and increased accumulation of cinnamate, coumarate, and ferulate derivatives concomitantly with a decrease in the levels of flavonols was observed, while the anticipated resveratrol or its derivatives were not detected. The changed metabolite profile suggested that chalcone synthase was down-regulated by the genetic modification; this was verified by decreased chalcone synthase transcript levels. Changes in the levels of phenolic compounds led to increased susceptibility of the transgenic strawberry to grey mould fungus.
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