Evidence map›Paper›PMID 19443122›Full record

ReviewUltramicroscopy2009

Atomic force microscopy: Unraveling the fundamental principles governing secretion and membrane fusion in cells.

Bhanu P Jena

Open access · greenAbstract readReview
In one paragraph

Review in Ultramicroscopy, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Bhanu P JenaDepartment of Physiology, Wayne State University School of Medicine, 5245 Scott Hall, Detroit, MI 48201, USA. bjena@med.wayne.edu
Wayne State University · US

Funding

UNDERSTANDING MEMBRANE FUSION A BIOENGINEERING APPROACHR01EB000303 · NIBIB · WAYNE STATE UNIVERSITY · PI JENA, BHANU P · 2002 to 2004
$1.2M
EXOCYTOSIS: USING NANOSURGERY AND BIOENGINEERINGR01DK056212 · NIDDK · YALE UNIVERSITY · PI JENA, BHANU P · 1999 to 2003
$1.1M
UNDERSTANDING MEMBRANE FUSION A BIOENGINEERING APPROACHR01NS039918 · NINDS · YALE UNIVERSITY · PI JENA, BHANU P · 2000 to 2001
$791k
NIBIB NIH HHS R01 EB000303NIDDK NIH HHS R01 DK056212NINDS NIH HHS R01 NS039918
6 · The paper itself

Abstract

The story of cell secretion and membrane fusion is as old as life itself. Without these fundamental cellular processes known to occur in yeast to humans, life would cease to exist. In the last 15 years, primarily using the atomic force microscope, a detailed understanding of the molecular process and of the molecular machinery and mechanism of secretion and membrane fusion in cells has come to light. This has led to a paradigm shift in our understanding of the underlying mechanism of cell secretion. The journey leading to the discovery of a new cellular structure the 'porosome',-the universal secretory machinery in cells, and the contributions of the AFM in our understanding of the general molecular machinery and mechanism of cell secretion and membrane fusion, is briefly discussed in this article.

Indexed as

Membrane FusionCell MembraneEukaryotic CellsMicroscopy, Atomic ForceProteinsProteins

Identifiers

PMID19443122
PMCPMC4580237
OpenAlexW1966063586

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.