ReviewCurrent hypertension reports2009
Central blood pressure, arterial stiffness, and wave reflection: new targets of treatment in essential hypertension.
Review in Current hypertension reports, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 53 citations in OpenAlex.
- Passive smoking and the risk of hypertension in nonsmoking adults: a systematic review and meta-analysis.PeerJ · 2026Pooled it
- Efficacy and safety of calcium channel blocker/diuretics combination therapy in hypertensive patients: a meta-analysis.Journal of clinical hypertension (Greenwich, Conn.) · 2015Pooled it
- Mediterranean-Style Diet Improves Systolic Blood Pressure and Arterial Stiffness in Older Adults.Hypertension (Dallas, Tex. : 1979) · 2019Trial
- Does stress from incarceration of family and friends contribute to signs of early vascular ageing in African American women?Journal of epidemiology and community health · 2024Article
- Central artery pulse pressure, not central arterial stiffness impact on all-cause mortality in patients with viral pneumonia infection.BMC infectious diseases · 2024Article
- Central Hemodynamics in African American Women: Examining the Role of Superwoman Schema Endorsement.Journal of the American Heart Association · 2024Article
- Effect of Different Classes of Antihypertensive Drugs on Arterial Stiffness.Current hypertension reports · 2023Review
- Improved arterial stiffness after combined aerobic and resistance training: correlation with heart rate variability change in prehypertensive offspring of hypertensive parents.Journal of exercise rehabilitation · 2022Article
- Changes in the Pulmonary Artery Wave Reflection in Dogs with Experimentally-Induced Acute Pulmonary Embolism and the Effect of Vasodilator.Animals : an open access journal from MDPI · 2021Article
- Effects of aerobic, resistance and concurrent exercise on pulse wave reflection and autonomic modulation in men with elevated blood pressure.Scientific reports · 2021Article
- A new approach to identifying hypertension-associated genes in the mesenteric artery of spontaneously hypertensive rats and stroke-prone spontaneously hypertensive rats.Journal of hypertension · 2019Article
- Arterial Stiffness Assessed by Cardio-Ankle Vascular Index.International journal of molecular sciences · 2019Review
- Measuring Central or Peripheral Blood Pressure Levels? That is the Question in the Modern Clinical Practice of Hypertension.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2018Article
- Impact of seasonality and air pollutants on carotid-femoral pulse wave velocity and wave reflection in hypertensive patients.PloS one · 2017Article
- A review of wave mechanics in the pulmonary artery with an emphasis on wave intensity analysis.Acta physiologica (Oxford, England) · 2016Review
- Interactions between macro- and micro-circulation: are they relevant?High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2015Review
- Predictive value of dynamic renal resistive index (DRIN) for renal outcome in type 2 diabetes and essential hypertension: a prospective study.Cardiovascular diabetology · 2015Observational
- Associations of serum uric acid levels with arterial wave reflections and central systolic blood pressure.International journal of cardiology · 2013Article
- Type 2 diabetes mellitus worsens arterial stiffness in hypertensive patients through endothelial dysfunction.Diabetologia · 2012Article
- Improvement of arterial stiffness by reducing oxidative stress damage in elderly hypertensive patients after 6 months of atorvastatin therapy.Journal of clinical hypertension (Greenwich, Conn.) · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Central blood pressure is dependent on the stiffness of large arteries and pulse wave reflection. These parameters are very important in the development of hypertensive target organ disease. Moreover, recent clinical studies have shown their independent predictive value for cardiovascular morbidity and mortality. Therefore, 2007 guidelines for the management of hypertension inserted the evaluation of central arterial stiffness as an important component for assessing total cardiovascular risk. Differences in the way various antihypertensive drugs affect arterial stiffness and central hemodynamics may explain the greater cardio-vascular protection provided by newer drugs (eg, renin-angiotensin system blockers or calcium channel blockers) independent of peripheral blood pressure reduction, as shown by recent clinical studies. However, the predictive value of the attenuation of arterial stiffness, wave reflections, and central blood pressure still needs to be confirmed in prospective, long-term, large-scale therapeutic trials. Thus, whether these measurements should be routinely performed as a diagnostic or therapeutic indicator remains debatable.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.