Evidence map›Paper›PMID 19440700›Full record

Trial reportPsychopharmacology2009

Global impairment of prospective memory following acute alcohol.

Julie R Leitz, Celia J A Morgan, James A Bisby, Peter G Rendell, H Valerie Curran

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Psychopharmacology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
4.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 77 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Episodic foresight is impaired following acute alcohol intoxication.Journal of psychopharmacology (Oxford, England) · 2023
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  18. A single dose of cocaine enhances prospective memory performance.Journal of psychopharmacology (Oxford, England) · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Julie R LeitzClinical Psychopharmacology Unit, Clinical Psychology, University College London, Gower St., London WC1E 6BT, UK. julieleitz@gmail.com
Celia J A Morgan
James A Bisby
Peter G Rendell
H Valerie Curran
UCL Australia · AUAustralian Catholic University · AUUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleWhilst the deleterious effects of alcohol on retrospective remembering have been widely documented, no study has yet objectively determined alcohol's effects on prospective memory (PM)--remembering to do something in the future.

objectivesWith this aim, the present study determined the acute effects of alcohol upon PM using a laboratory measure that simulates the PM tasks in everyday life--'Virtual Week'--both (a) in its standard form with regular, irregular, event-based and time-based PM tasks; and (b) an adapted version which enabled exploration of how future event simulation at encoding impacted upon subsequent PM.

methodsForty healthy volunteers were administered 0.6 g/kg ethanol or a matched placebo in a double-blind fashion and completed the two versions of Virtual Week along with prose recall (to tap retrospective memory) and an executive function task.

resultsAlcohol acutely produced global impairments across all (regular, irregular, event-based and time-based) PM tasks. It also produced impairments of episodic memory which positively correlated with PM performance of irregular tasks. Future-event simulation tended to enhance PM in the placebo but not in the alcohol group.

conclusionsThese findings on an objective measure of PM suggest that 4-5 units of alcohol will compromise PM abilities in everyday life.

Indexed as

AdultAwarenessCentral Nervous System DepressantsDose-Response Relationship, DrugDouble-Blind MethodEthanolFemaleHumansMaleMemoryMental RecallTime FactorsCentral Nervous System DepressantsEthanol

Identifiers

PMID19440700
OpenAlexW2080429507

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.