Evidence map›Paper›PMID 19440275›Full record

ArticleInternational journal of environmental research and public health2009

Vitamin D status of clinical practice populations at higher latitudes: analysis and applications.

Stephen J Genuis, Gerry K Schwalfenberg, Michelle N Hiltz, Sharon A Vaselenak

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Vitamin D and Chronic Diseases.Aging and disease · 2017
    Review
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  11. Prevalence of vitamin D insufficiency and associated factors among Canadian Cree: a cross-sectional study.Canadian journal of public health = Revue canadienne de sante publique · 2013
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  18. Clinical utility of vitamin d testing: an evidence-based analysis.Ontario health technology assessment series · 2010
    Article
  19. Th17 mediators and vitamin D status in influenza A (H1N1).Critical care (London, England) · 2010
    Article
  20. Vitamin D Deficiency: Is The Pandemic for Real?Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Stephen J GenuisUniversity of Alberta, Edmonton Alberta, Canada. sgenuis@ualberta.ca
Gerry K Schwalfenberg
Michelle N Hiltz
Sharon A Vaselenak

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInadequate levels of vitamin D (VTD) throughout the life cycle from the fetal stage to adulthood have been correlated with elevated risk for assorted health afflictions. The purpose of this study was to ascertain VTD status and associated determinants in three clinical practice populations living in Edmonton, Alberta, Canada--a locale with latitude of 53 degrees 30'N, where sun exposure from October through March is often inadequate to generate sufficient vitamin D.

methodsTo determine VTD status, 1,433 patients from three independent medical offices in Edmonton had levels drawn for 25(OH)D as part of their medical assessment between Jun 2001 and Mar 2007. The relationship between demographic data and lifestyle parameters with VTD status was explored. 25(OH)D levels were categorized as follows: (1) Deficient: <40 nmol/L; (2) Insufficient (moderate to mild): 40 to <80 nmol/L; and (3) Adequate: 80-250 nmol/L. Any cases <25 nmol/L were subcategorized as severely deficient for purposes of further analysis.

results240 (16.75% of the total sample) of 1,433 patients were found to be VTD 'deficient' of which 48 (3.35% of the overall sample) had levels consistent with severe deficiency. 738 (51.5% of the overall sample) had 'insufficiency' (moderate to mild) while only 31.75% had 'adequate' 25(OH)D levels. The overall mean for 25(OH) D was 68.3 with SD=28.95. VTD status was significantly linked with demographic and lifestyle parameters including skin tone, fish consumption, milk intake, sun exposure, tanning bed use and nutritional supplementation.

conclusionA high prevalence of hypovitaminosis-D was found in three clinical practice populations living in Edmonton. In view of the potential health sequelae associated with widespread VTD inadequacy, strategies to facilitate translation of emerging epidemiological information into clinical intervention need to be considered in order to address this public health issue. A suggested VTD supplemental intake level is presented for consideration.

Indexed as

AdultAlbertaFemaleGeographyHumansMaleMiddle AgedVitamin DVitamin D DeficiencyYoung AdultVitamin DDietary supplementsepidemiologyhypovitaminosis-Dinformation scienceknowledge translationnutritionpublic healthvitamin Dvitamin D deficiencyvitamin D insufficiency

Identifiers

PMID19440275
PMCPMC2672339

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.