ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Type 2 diabetes is associated with more advanced coronary atherosclerosis on multislice computed tomography and virtual histology intravascular ultrasound.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Plaque volume and plaque risk profile in diabetic vs. non-diabetic patients undergoing lipid-lowering therapy: a study based on 3D intravascular ultrasound and virtual histology.Cardiovascular diabetology · 2017Trial
- Coronary aspirate TNFα reflects saphenous vein bypass graft restenosis risk in diabetic patients.Cardiovascular diabetology · 2013Trial
- Long-Term Outcomes Following Percutaneous Coronary Intervention With Rotational Atherectomy for Severely Calcified Lesions.Circulation reports · 2025Article
- Atherosclerotic plaque characteristics on quantitative coronary computed tomography angiography associated with ischemia on positron emission tomography in diabetic patients.The international journal of cardiovascular imaging · 2022Article
- Coronary computed tomography angiography as a tool for long-term cardiovascular risk stratification in diabetic patients.Heart and vessels · 2019Article
- Mechanisms of Vascular Calcification: The Pivotal Role of Pyruvate Dehydrogenase Kinase 4.Endocrinology and metabolism (Seoul, Korea) · 2016Review
- Prognostic value of coronary computed tomography angiography in diabetic patients without chest pain syndrome.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Article
- Serum Total Bilirubin Levels Provide Additive Risk Information over the Framingham Risk Score for Identifying Asymptomatic Diabetic Patients at Higher Risk for Coronary Artery Stenosis.Diabetes & metabolism journal · 2015Article
- Inflammation: a culprit for vascular calcification in atherosclerosis and diabetes.Cellular and molecular life sciences : CMLS · 2015Review
- Everolimus Eluting Stents Versus Coronary Artery Bypass Graft Surgery for Patients With Diabetes Mellitus and Multivessel Disease.Circulation. Cardiovascular interventions · 2015Article
- Coronary artery disease in patients with atypical chest pain with and without diabetes mellitus assessed with coronary CT angiography.BMJ open diabetes research & care · 2014Article
- Impact of prediabetic status on coronary atherosclerosis: a multivessel angioscopic study.Diabetes care · 2013Article
- Diagnosis of coronary artery disease in persons with diabetes mellitus.Current diabetes reports · 2012Article
- MESA: the NIH-sponsored study that validates atherosclerosis imaging for primary prevention.Current atherosclerosis reports · 2011Article
- Comprehensive assessment of spotty calcifications on computed tomography angiography: comparison to plaque characteristics on intravascular ultrasound with radiofrequency backscatter analysis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2011Article
- The impact of macrophage insulin resistance on advanced atherosclerotic plaque progression.Circulation research · 2010Review
- [Revascularization of coronary artery disease in diabetes mellitus].Wiener medizinische Wochenschrift (1946) · 2010Review
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Abstract
backgroundData on coronary plaque observations on multi-slice computed tomography (MSCT) in patients with type 2 diabetes are scarce. METHODS AND
resultsIn total, 60 patients (19 with diabetes) underwent 64-slice MSCT, followed by conventional coronary angiography with intravascular ultrasound (IVUS). Non-invasively, the extent of coronary atherosclerosis and 3 plaque types (non-calcified, calcified, mixed) were visually evaluated on MSCT. Invasively, plaque burden was assessed on gray-scale IVUS. Plaque composition was evaluated on virtual histology intravascular ultrasound (VH IVUS). Concerning geometrical plaque data, diabetic patients showed more plaques on MSCT (7.1 +/- 3.2 vs 4.9 +/- 3.2 in non-diabetic patients, P = .01). On gray-scale IVUS, diabetes was associated with a larger plaque burden (48.7 +/- 10.7% vs 40.0 +/- 12.1%, P = .003). Concerning plaque composition, diabetes was associated with more calcified plaques on MSCT (52% vs 24%). Relatively more fibrocalcific plaques in diabetic patients (29% versus 9%) were observed on VH IVUS. Moreover, these plaques contained more necrotic core (10.8 +/- 5.9% vs 8.6 +/- 5.2%, P = .01).
conclusionA higher plaque extent and more calcified lesions were observed in diabetic patients on MSCT. The findings were confirmed on gray-scale and VH IVUS. Thus, MSCT may potentially be used to explore patterns of coronary atherosclerosis in diabetic patients.
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