ArticlePloS one2009
Chimpanzee malaria parasites related to Plasmodium ovale in Africa.
Article in PloS one, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
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Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.
- The threat of increased transmission of non-Parasitology · 2023Pooled it
- The Genome of Plasmodium gonderi: Insights into the Evolution of Human Malaria Parasites.Genome biology and evolution · 2024Article
- Why Plasmodium vivax and Plasmodium falciparum are so different? A tale of two clades and their species diversities.Malaria journal · 2022Review
- The primate malaria parasites Plasmodium malariae, Plasmodium brasilianum and Plasmodium ovale spp.: genomic insights into distribution, dispersal and host transitions.Malaria journal · 2022Review
- Zoonotic Transmissions and Host Switches of Malaria Parasites.Zoonoses (Shannon, Ireland) · 2021Article
- Ape Origins of Human Malaria.Annual review of microbiology · 2020Review
- A review of research in primate sanctuaries.Biology letters · 2020Review
- Parasite-Host Interaction and Pathophysiology Studies of the Human Relapsing MalariasFrontiers in cellular and infection microbiology · 2020Review
- Plasmodium ovale wallikeri in Western Lowland Gorillas and Humans, Central African Republic.Emerging infectious diseases · 2018Article
- Investigating zoonotic infection barriers to ape Plasmodium parasites using faecal DNA analysis.International journal for parasitology · 2018Article
- Malaria parasites of long-tailed macaques in Sarawak, Malaysian Borneo: a novel species and demographic and evolutionary histories.BMC evolutionary biology · 2018Article
- Wild African great apes as natural hosts of malaria parasites: current knowledge and research perspectives.Primate biology · 2017Review
- Investigation on possible transmission of monkeys' Plasmodium to human in a populations living in the equatorial rainforest of the Democratic republic of Congo.International journal for parasitology. Parasites and wildlife · 2016Article
- Primate malarias: Diversity, distribution and insights for zoonoticOne health (Amsterdam, Netherlands) · 2015Article
- Molecular characterization of misidentified Plasmodium ovale imported cases in Singapore.Malaria journal · 2015Article
- Mosquitocidal and antibacterial activity of green-synthesized silver nanoparticles from Aloe vera extracts: towards an effective tool against the malaria vector Anopheles stephensi?Parasitology research · 2015Article
- Diversity of malaria parasites in great apes in Gabon.Malaria journal · 2015Article
- The origins of malaria: there are more things in heaven and earth ….Parasitology · 2015Review
- Recent advances in detection of Plasmodium ovale: implications of separation into the two species Plasmodium ovale wallikeri and Plasmodium ovale curtisi.Journal of clinical microbiology · 2014Review
- Real-time PCR assay for discrimination of Plasmodium ovale curtisi and Plasmodium ovale wallikeri in the Ivory Coast and in the Comoros Islands.Malaria journal · 2012Article
Corrections and comments
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Authors and funding
9 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since the 1970's, the diversity of Plasmodium parasites in African great apes has been neglected. Surprisingly, P. reichenowi, a chimpanzee parasite, is the only such parasite to have been molecularly characterized. This parasite is closely phylogenetically related to P. falciparum, the principal cause of the greatest malaria burden in humans. Studies of malaria parasites from anthropoid primates may provide relevant phylogenetic information, improving our understanding of the origin and evolutionary history of human malaria species. In this study, we screened 130 DNA samples from chimpanzees (Pan troglodytes) and gorillas (Gorilla gorilla) from Cameroon for Plasmodium infection, using cytochrome b molecular tools. Two chimpanzees from the subspecies Pan t. troglodytes presented single infections with Plasmodium strains molecularly related to the human malaria parasite P. ovale. These chimpanzee parasites and 13 human strains of P. ovale originated from a various sites in Africa and Asia were characterized using cytochrome b and cytochrome c oxidase 1 mitochondrial partial genes and nuclear ldh partial gene. Consistent with previous findings, two genetically distinct types of P. ovale, classical and variant, were observed in the human population from a variety of geographical locations. One chimpanzee Plasmodium strain was genetically identical, on all three markers tested, to variant P. ovale type. The other chimpanzee Plasmodium strain was different from P. ovale strains isolated from humans. This study provides the first evidence of possibility of natural cross-species exchange of P. ovale between humans and chimpanzees of the subspecies Pan t. troglodytes.
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