ArticleTherapeutics and clinical risk management2009
Angioid streaks, clinical course, complications, and current therapeutic management.
Article in Therapeutics and clinical risk management, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
What it found
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The trial behind it
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Who cites it
53 citing papers in PubMed, 101 citations in OpenAlex.
- The role of multimodal imaging in characterization and monitoring of choroidal neovascularization secondary to angioid streaks.European journal of ophthalmology · 2025Article
- Angioid Streaks and Choroidal Neovascular Membrane Secondary to Pseudoxanthoma Elasticum: A Case Report.Cureus · 2024Article
- Angioid Streaks Remain a Challenge in Diagnosis, Management, and Treatment.Vision (Basel, Switzerland) · 2024Review
- Article
- Novel Human Induced Pluripotent Stem Cell-Based Model for Retinal Pigment Epithelial Cells to Reveal Possible Disease Mechanisms for Macular Degeneration in Pseudoxanthoma Elasticum.Journal of ophthalmology · 2024Article
- Systemic disease associations with angioid streaks in a large healthcare claims database.Eye (London, England) · 2023Article
- Central serous chorioretinopathy and angioid streaks: coincidental?BMC ophthalmology · 2022Article
- Intravitreal Brolucizumab for Choroidal Neovascularization Associated to Angioid Streaks.Case reports in ophthalmological medicine · 2022Article
- Long-Term Effect of Anti-Vascular Endothelial Growth Factor (Anti-VEGF) Injections in Choroidal Neovascularization Secondary to Angioid Streaks.Journal of ophthalmology · 2022Article
- Clinical Characterization of Korean Patients with Pseudoxanthoma Elasticum and Angioid Streaks.Genes · 2021Observational
- Angioid Streaks in Pseudoxanthoma Elasticum.Cureus · 2021Article
- Angioid streaks and obstructive sleep apnea syndrome: are they related?Sleep & breathing = Schlaf & Atmung · 2021Article
- Pattern dystrophy-like changes and coquille d'oeuf atrophy in elderly patients affected by pseudoxanthoma elasticum.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020Article
- Ocular abnormalities in beta thalassemia patients: prevalence, impact, and management strategies.International ophthalmology · 2020Review
- Multimodal imaging of angioid streaks.GMS ophthalmology cases · 2020Article
- Clinical characteristics and treatment outcomes of angioid streak associated choroidal neovascular membrane (AS-CNV): a Zambian case series.The Pan African medical journal · 2020Article
- Retinal sensitivity in angioid streaks.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2019Observational
- Whole exome sequencing identified three ABCC6 variants in two Pakistani families with pseudoxanthoma elasticum phenotype.Molecular biology reports · 2019Article
- Evaluation of macular and peripapillary choroidal thickness, macular volume and retinal nerve fiber layer in acromegaly patients.International ophthalmology · 2018Article
- Subretinal fibrosis is associated with fundus pulverulentus in pseudoxanthoma elasticum.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2018Observational
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Angioid streaks are visible irregular crack-like dehiscences in Bruch's membrane that are associated with atrophic degeneration of the overlying retinal pigmented epithelium. Angioid streaks may be associated with pseudoxanthoma elasticum, Paget's disease, sickle-cell anemia, acromegaly, Ehlers-Danlos syndrome, and diabetes mellitus, but also appear in patients without any systemic disease. Patients with angioid streaks are generally asymptomatic, unless the lesions extend towards the foveola or develop complications such as traumatic Bruch's membrane rupture or macular choroidal neovascularization (CNV). The visual prognosis in patients with CNV secondary to angioid streaks if untreated, is poor and most treatment modalities, until recently, have failed to limit the devastating impact of CNV in central vision. However, it is likely that treatment with antivascular endothelial growth factor, especially in treatment-naive eyes to yield favorable results in the future and this has to be investigated in future studies.
Identifiers
19436620PMC2697526W2122178465What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.