Is the gamma interferon assay in cattle influenced by multiple tuberculin injections?

Sheila A Rangen, Om P Surujballi, Cyril Lutze-Wallace, V Wayne Lees

Open access · greenAbstract readComparative Study

In one paragraph

Article in The Canadian veterinary journal = La revue veterinaire canadienne, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.3field-weighted citation impact, top 42% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

A review of risk factors for bovine tuberculosis infection in cattle in the UK and Ireland.Epidemiology and infection · 2016
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sheila A RangenLomsnes Veterinary Hospital, 3450-50 Avenue, Red Deer, Alberta T4N 3Y4, Canada. sar135@mail.usask.ca

Om P Surujballi

Cyril Lutze-Wallace

V Wayne Lees

Red Deer Regional Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Along with other developed countries, Canada is interested in adopting the gamma interferon (IFN-gamma) assay to test for bovine tuberculosis (TB). This study compared results of using the IFN-gamma assay in a large number of field-tested cattle in Manitoba, some previously tested with a caudal fold test (CFT) only, and others injected with tuberculins for both a CFT and a comparative cervical test (CCT). Parallel testing further compared the IFN-gamma assay and CCT results with the confirmed TB status of the animal (culture, histopathologic examination, polymerase chain reaction). Results from IFN-gamma assays did not differ following the CFT versus CFT and CCT injections. Parallel testing demonstrated an apparent higher prevalence of tuberculosis for the IFN-gamma assay versus CCT, which will assist in earlier removal of exposed animals and, ultimately, prevent populations from becoming infected.

Indexed as

TuberculinAnimalsAntigens, BacterialCattleFemaleInterferon-gammaMaleManitobaMycobacterium bovisPolymerase Chain ReactionSensitivity and SpecificitySkin TestsTuberculin TestTuberculosis, BovineAntigens, BacterialInterferon-gammaTuberculin

Identifiers

PMID19436478

PMCPMC2643450

OpenAlexW1500237771

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.