Evidence map›Paper›PMID 19435455›Full record

ReviewExpert review of molecular diagnostics2009

Current advances in research and clinical applications of PLGA-based nanotechnology.

Jian-Ming Lü, Xinwen Wang, Christian Marin-Muller, Hao Wang, Peter H Lin, Qizhi Yao, Changyi Chen

Abstract readReview
In one paragraph

Review in Expert review of molecular diagnostics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 307 papers.

0numbers the graph read from it
0cells of the map it votes in
307citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

307 citing papers in PubMed.

  1. Review
  2. Intraorgan and targeted nanodelivery in organ transplantation of nonhuman primates.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Tissue-specific gene delivery approaches.Bioengineering & translational medicine · 2026
    Review
  7. Review
  8. Article
  9. Article
  10. Advanced Human Immune Cell-Organoid Co-Cultures for Functional Testing of Cancer Nanovaccines.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Tailoring the Release of Paclitaxel from Electrospun Nonwovens.International journal of molecular sciences · 2025
    Article
  19. Article
  20. Review

247 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jian-Ming LüMichael E DeBakey Department of Surgery, Division of Vascular Surgery and Endovascular Therapy, Baylor College of Medicine, Houston, TX 77030, USA.
Xinwen Wang
Christian Marin-Muller
Hao Wang
Peter H Lin
Qizhi Yao
Changyi Chen

Funding

Tissue engineering of small diameter vascular graftR01EB002436 · NIBIB · BAYLOR COLLEGE OF MEDICINE · PI CHEN, CHANGYI · 2003 to 2006
$1.8M
NIBIB NIH HHS EB002436NIBIB NIH HHS R01 EB002436
6 · The paper itself

Abstract

Co-polymer poly(lactic-co-glycolic acid) (PLGA) nanotechnology has been developed for many years and has been approved by the US FDA for the use of drug delivery, diagnostics and other applications of clinical and basic science research, including cardiovascular disease, cancer, vaccine and tissue engineering. This article presents the more recent successes of applying PLGA-based nanotechnologies and tools in these medicine-related applications. It focuses on the possible mechanisms, diagnosis and treatment effects of PLGA preparations and devices. This updated information will benefit to both new and established research scientists and clinical physicians who are interested in the development and application of PLGA nanotechnology as new therapeutic and diagnostic strategies for many diseases.

Indexed as

Drug Delivery SystemsLactic AcidPolyglycolic AcidAbsorbable ImplantsAnimalsBiocompatible MaterialsHumansMaterials TestingNanoparticlesNanotechnologyPolylactic Acid-Polyglycolic Acid CopolymerTissue EngineeringBiocompatible MaterialsLactic AcidPolyglycolic AcidPolylactic Acid-Polyglycolic Acid Copolymer

Identifiers

PMID19435455
PMCPMC2701163

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.