Evidence map›Paper›PMID 19433244›Full record

ReviewMolecular and cellular endocrinology2009

Endocrine disrupters as obesogens.

Felix Grün, Bruce Blumberg

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Molecular and cellular endocrinology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 218 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
218citing papers in PubMed, 9 pooled it
18.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

218 citing papers in PubMed, 9 syntheses or guidelines pooled it, 573 citations in OpenAlex.

  1. Pooled it
  2. Pollution, stress response, and obesity: A systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
    Pooled it
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  5. Prenatal exposure to persistent organic pollutants and childhood obesity: A systematic review and meta-analysis of human studies.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2022
    Pooled it
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  10. Trial
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158 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Felix GrünDepartment of Developmental & Cell Biology, University of California Irvine, 92697-2300, USA.
Bruce Blumberg
University of California, Irvine · US

Funding

Endocrine disruption by organotins in obesity and diabetesR01ES015849 · NIEHS · UNIVERSITY OF CALIFORNIA-IRVINE · PI BLUMBERG, BRUCE · 2007 to 2011
$2.2M
NIEHS NIH HHS R01 ES015849
6 · The paper itself

Abstract

The recent dramatic rise in obesity rates is an alarming global health trend that consumes an ever increasing portion of health care budgets in Western countries. The root cause of obesity is thought to be a prolonged positive energy balance. Hence, the major focus of preventative programs for obesity has been to target overeating and inadequate physical exercise. Recent research implicates environmental risk factors, including nutrient quality, stress, fetal environment and pharmaceutical or chemical exposure as relevant contributing influences. Evidence points to endocrine disrupting chemicals that interfere with the body's adipose tissue biology, endocrine hormone systems or central hypothalamic-pituitary-adrenal axis as suspects in derailing the homeostatic mechanisms important to weight control. This review highlights recent advances in our understanding of the molecular targets and mechanisms of action for these compounds and areas of future research needed to evaluate the significance of their contribution to obesity.

Indexed as

AnimalsCaloric RestrictionEndocrine DisruptorsEndocrine SystemEnergy MetabolismEnvironmental ExposureEnvironmental PollutantsGonadal Steroid HormonesHumansObesityPeroxisome Proliferator-Activated ReceptorsRetinoid X ReceptorsEndocrine DisruptorsEnvironmental PollutantsGonadal Steroid HormonesPeroxisome Proliferator-Activated ReceptorsRetinoid X Receptors

Identifiers

PMID19433244
PMCPMC2713042
OpenAlexW2117923938

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.