Evidence map›Paper›PMID 19432387›Full record

ReviewDialogues in clinical neuroscience2009

Characteristics, correlates, and outcomes of childhood and adolescent depressive disorders.

Uma Rao, Li-Ann Chen

Open access · diamondAbstract readReview
PubMed Full text at PMC
In one paragraph

Review in Dialogues in clinical neuroscience, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
96citing papers in PubMed, 4 pooled it
16.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

96 citing papers in PubMed, 4 syntheses or guidelines pooled it, 268 citations in OpenAlex.

  1. Pooled it
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  3. Social isolation and its impact on child and adolescent development: a systematic review.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2021
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36 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Uma RaoDepartment of Psychiatry, the University of Texas Southwestern Medical Center, Dallas, Texas 75390-9101, USA. uma.rao@utsouthwestern.edu
Li-Ann Chen
The University of Texas Southwestern Medical Center · US

Funding

Risk for Substance Abuse in Depressed AdolescentsR01MH062464 · NIMH · UT SOUTHWESTERN MEDICAL CENTER · PI RAO, UMA · 2001 to 2006
$2.4M
Stress Response and Smoking Cessation in Depressed YouthR01DA015131 · NIDA · UT SOUTHWESTERN MEDICAL CENTER · PI RAO, UMA · 2003 to 2007
$2.4M
Markers of Risk for Nicotine Dependence in YoungstersR01DA014037 · NIDA · UT SOUTHWESTERN MEDICAL CENTER · PI RAO, UMA · 2001 to 2006
$1.9M
Treatment Prediction in Adolescent and Adult DepressionR01MH068391 · NIMH · UT SOUTHWESTERN MEDICAL CENTER · PI RAO, UMA · 2004 to 2012
$1.7M
Stress and Risk for Substance Abuse in AdolescentsR01DA017804 · NIDA · UT SOUTHWESTERN MEDICAL CENTER · PI RAO, UMA · 2004 to 2008
$1.6M
Neuronal Risk Markers for Nicotine Dependence in YouthR01DA017805 · NIDA · UT SOUTHWESTERN MEDICAL CENTER · PI RAO, UMA · 2004 to 2010
$1.4M
NIDA NIH HHS DA14037NIDA NIH HHS DA15131NIDA NIH HHS DA17804NIDA NIH HHS DA17805NIDA NIH HHS R01 DA014037NIDA NIH HHS R01 DA015131NIDA NIH HHS R01 DA017804NIDA NIH HHS R01 DA017805NIMH NIH HHS MH62464NIMH NIH HHS MH68391NIMH NIH HHS R01 MH062464NIMH NIH HHS R01 MH068391
6 · The paper itself

Abstract

Depressive illness beginning early in life can have serious developmental and functional consequences. Therefore, understanding the disorder during this developmental stage is critical for determining its etiology and course, as well as for developing effective intervention strategies. This paper summarizes current knowledge regarding the etiology, phenomenology, correlates, natural course, and consequences of unipolar depression in children and adolescents. Using adult depression as a framework, the unique aspects of childhood and adolescence are considered in order to better understand depression within a developmental context. The data suggest that the clinical presentation, correlates, and natural course of depression are remarkably similar across the lifespan. There are, however, important developmental differences. Specifically, the familial and psychological context in which depression develops in youngsters is associated with variability in the frequency and nature of depressive symptoms and comorbid conditions among children and adolescents. Maturational differences have also been identified in the neurobiological correlates of depression. These developmental differences may be associated with the observed variability in clinical response to treatment and longitudinal course. Characterization of the developmental differences will be helpful in developing more specific and effective interventions for youngsters, thereby allowing them to reach their full potential as adults.

Indexed as

AdolescentAgingBrainCausalityChildComorbidityDepressive DisorderFemaleHumansMaleSex DistributionSocial BehaviorStress, Psychological

Identifiers

PMID19432387
PMCPMC2766280
OpenAlexW1519727848

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.