ArticleMolecular biology reports2010
Glutathione S-transferase genetic polymorphisms (GSTM1, GSTT1 and GSTO2) in three Iranian populations.
Article in Molecular biology reports, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.
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Who cites it
46 citing papers in PubMed, 3 syntheses or guidelines pooled it, 85 citations in OpenAlex.
- Genetic Polymorphism of CAT C-262 T and Susceptibility to Breast Cancer, a Case-Control Study and Meta-Analysis of the Literatures.Pathology oncology research : POR · 2015Pooled it
- Association of GSTM1 null allele with prostate cancer risk: evidence from 36 case-control studies.PloS one · 2012Pooled it
- Genetic polymorphisms of glutathione S-transferase M1 and bladder cancer risk: a meta-analysis of 26 studies.Molecular biology reports · 2011Pooled it
- Association between human telomerase reverse transcriptase (hTERT) MNS16A polymorphism and risk of breast cancer.Molecular biology reports · 2024Article
- Association between rs3761548 polymorphism ofMolecular biology research communications · 2024Article
- Susceptibility to preeclampsia is associated with a 50-bp insertion/deletion polymorphism at the promoter region of theJournal of the Turkish German Gynecological Association · 2021Article
- Association between three common genetic polymorphisms ofEXCLI journal · 2021Article
- Association of Glutathione S-TransferaseReports of biochemistry & molecular biology · 2020Article
- Association between Genetic Polymorphisms in Superoxide Dismutase Gene Family and Risk of Gastric Cancer.Pathology oncology research : POR · 2020Article
- Genetic Polymorphisms of Glutathione S-Transferases T1 (Iranian journal of public health · 2019Article
- The status ofMedical journal of the Islamic Republic of Iran · 2019Article
- Association between a 50bp Ins/Del polymorphism at the promoter region of the superoxide dismutase-1 and age of onset of schizophrenia.EXCLI journal · 2019Article
- Genetic polymorphisms of superoxide dismutase-1 A251G and catalase C-262T with the risk of colorectal cancer.Molecular biology research communications · 2017Article
- Association between ABO and Rh Blood Groups and Risk of Preeclampsia: A Case-Control Study from Iran.Open access Macedonian journal of medical sciences · 2017Article
- Influence of a 50bp Ins/Del polymorphism at promoter of the superoxide dismutase-1 on gene expression and risk of heroin dependency.Environmental health and preventive medicine · 2017Article
- Association of glutathione S-transferase polymorphisms with the severity of mustard lung.BioImpacts : BI · 2017Article
- Influence of A-21T and C-262T genetic polymorphisms at the promoter region of the catalase (CAT) on gene expression.Environmental health and preventive medicine · 2016Article
- Susceptibility to Ulcerative Colitis and Genetic Polymorphisms of A251G SOD1 and C-262T CAT.Journal of medical biochemistry · 2016Article
- No association betweenMolecular biology research communications · 2016Article
- Association of glutathione S-transferases M1 and T1 gene polymorphisms with the risk of metabolic syndrome in an Iranian population.Advanced biomedical research · 2016Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Genetic polymorphisms in genes encoding glutathione S-transferases M1 (GSTM1; a member of class mu), T1 (GSTT1; a member of class theta) and O2 (GSTO2; a member of class omega) have been defined previously. Studies have revealed that there were significant differences between populations for allelic frequencies of GSTT1, GSTM1 and GSTO2 N412D polymorphisms. To get more insight into the genetic structure of Iranian populations the present study was done on Iranian Georgians living in Frydoonshahr (Isfahan province) and two Persian populations who living in Shiraz (Fars province) and Frydoonshahr. Study subjects consisted of 401 unrelated healthy individuals. From these 121 were Georgians. The remaining subjects were Persians from either Frydoonshahr (n = 34) or Shiraz (n = 246). The genetic polymorphism of GSTT1, GSTM1 and GSTO2 N412D was detected by PCR-based method. The frequency of GSTT1 null genotype in Georgian and Persians of Frydoonshahr and Shiraz was 15.7, 35.2 and 24.8%, respectively. There was significant difference between these populations for the distributions of the GSTT1 genotypes (chi(2) = 7.00, df = 2, P = 0.030). No significant difference was observed between these populations for polymorphisms of GSTM1 (chi(2) = 1.682, df = 2, P = 0.431) and GSTO N142D (chi(2) = 4.622, df = 4, P = 0.328). The prevalence of GSTT1 null genotype in Iranian Georgians showed significant difference with Persians and other Asian countries, but it seems to be similar with the frequency which was reported from European populations.
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