Evidence map›Paper›PMID 19430946›Full record

Trial reportEuropean journal of applied physiology2009

Effects of acute hypoxia tests on blood markers in high-level endurance athletes.

Rémi Mounier, Vincent Pialoux, Laurent Schmitt, Jean-Paul Richalet, Paul Robach, Jean Coudert, Eric Clottes, Nicole Fellmann

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rémi MounierLaboratoire de Biologie des Activités Physiques et Sportives, Faculté de Médecine, 63000 Clermont-Ferrand, France. remimounier@voila.fr
Vincent Pialoux
Laurent Schmitt
Jean-Paul Richalet
Paul Robach
Jean Coudert
Eric Clottes
Nicole Fellmann

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to determine the response of blood markers to acute hypoxia in high-level endurance athletes before training based on "living high-training low" model. Thirty endurance athletes performed a hypoxic cycling test and spent 3 h at rest in a simulated altitude of 3,000 m. At the end of the hypoxic cycling test, the quantity of the natural antisense transcript of HIF-1alpha mRNA (aHIF) transcript increased significantly (+37%, P = 0.024). After 3-h exposure, at a simulated altitude of 3,000 m, the amount of HIF-1alpha mRNA increased significantly (+57%, P = 0.012). Moreover, a large inter-subject range was observed in response to the hypoxic cycling test and to the prolonged hypoxic exposure: -133%/+79% and -82%/+653% for HIF-1alpha mRNA, 69%/+324% and -76%/+229% for aHIF. This study shows a large inter-variability of blood markers in elite athletes in response to acute hypoxic exposure corroborating previous observations made in other populations.

Indexed as

Exercise TestAdolescentAdultArteriesBiomarkersBlood Chemical AnalysisFemaleHeart RateHumansHypoxiaHypoxia-Inducible Factor 1, alpha SubunitLeukocytesMaleOxygen ConsumptionPhysical EnduranceSportsBiomarkersHIF1A protein, humanHypoxia-Inducible Factor 1, alpha Subunit

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.