ArticleEuropean journal of pediatrics2010
Primary peritonitis in children with nephrotic syndrome: results of a 5-year multicenter study.
Article in European journal of pediatrics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 65 citations in OpenAlex.
- IPNA clinical practice recommendations for the diagnosis and management of children with steroid-resistant nephrotic syndrome.Pediatric nephrology (Berlin, Germany) · 2020Guideline
- The Italian Society for Pediatric Nephrology (SINePe) consensus document on the management of nephrotic syndrome in children: Part I - Diagnosis and treatment of the first episode and the first relapse.Italian journal of pediatrics · 2017Pooled it
- Clinical practice guideline for pediatric idiopathic nephrotic syndrome 2013: general therapy.Clinical and experimental nephrology · 2015Guideline
- Pneumococcal carriage and serotype distribution in children with nephrotic syndrome.Pediatric nephrology (Berlin, Germany) · 2024Article
- Guidelines for Antibiotics Prescription in Critically Ill Patients.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024Article
- Hypomethylation of NLRP3 gene promoter discriminates glucocorticoid-resistant from glucocorticoid-sensitive idiopathic nephrotic syndrome patients.Clinical and translational science · 2021Observational
- Spontaneous Bacterial Peritonitis in an Adult Patient with Minimal Change Disease.The American journal of case reports · 2021Article
- Pediatric Immunization Practices in Nephrotic Syndrome: An Assessment of Provider and Parental Knowledge.Frontiers in pediatrics · 2020Article
- Steroid-Associated Side Effects in Patients With Primary Proteinuric Kidney Disease.Kidney international reports · 2019Article
- Guidelines for Antibiotic Prescription in Intensive Care Unit.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2019Article
- Safety and Efficacy of Pneumococcal Vaccination in Pediatric Nephrotic Syndrome.Frontiers in pediatrics · 2019Review
- The non-immunosuppressive management of childhood nephrotic syndrome.Pediatric nephrology (Berlin, Germany) · 2016Review
- Pneumococcal hemolytic uremic syndrome and steroid resistant nephrotic syndrome.Clinical kidney journal · 2016Article
- Increasing frequency of acute kidney injury amongst children hospitalized with nephrotic syndrome.Pediatric nephrology (Berlin, Germany) · 2014Article
- Serum albumin level accurately reflects antioxidant potentials in idiopathic nephrotic syndrome.Clinical and experimental nephrology · 2012Article
- Chapter 4: Steroid-resistant nephrotic syndrome in children.Kidney international supplements · 2012Article
- Incidence and risk factors for major infections in hospitalized children with nephrotic syndrome.Jornal brasileiro de nefrologiaObservational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 8 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary peritonitis is a well-described infectious complication of nephrotic syndrome. Current data on the true incidence of peritonitis and efficacy of preventive pneumococcal vaccination are not clear in this group of children. In this nationwide study, among a total of 268 patients with an initial diagnosis of steroid sensitive nephrotic syndrome, eight episodes of primary peritonitis were detected in seven patients during 5 years. All eight attacks of peritonitis occurred in the relapse period. Seven of these peritonitis episodes occurred in the first 2 years of nephrotic syndrome, three of them during the first attack. One patient had two attacks with a 6-month interval. Only two of the patients were steroid sensitive, while four of them were steroid dependent, and one was steroid resistant at the diagnosis of peritonitis. The causing microorganism was identified in three patients (Streptococcus hemolyticus, Streptococcus pneumoniae, and alpha-hemolytic Streptococcus). Incidence of peritonitis (2.6%) in our series was not high when compared with previous reports. None of the patients had been immunized against pneumococcus before or after the peritonitis attack. It raises the question if the vaccine is necessary for every child with steroid sensitive nephrotic syndrome. However, we suggest that immunization against pneumococcus is not indicated in children with steroid-responsive nephrotic syndrome (NS) and should be reserved for the small number of children who have steroid-dependent or steroid-resistant NS.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.