Trial reportLasers in medical science2010
Capacity of photodynamic therapy for microbial reduction in periodontal pockets.
Trial report in Lasers in medical science, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 61 citations in OpenAlex.
- Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri-implant diseases.The Cochrane database of systematic reviews · 2024Pooled it
- Photodynamic therapy in the treatment of chronic periodontitis: a systematic review and meta-analysis.Lasers in medical science · 2013Pooled it
- Additional effects of aPDT on nonsurgical periodontal treatment with doxycycline in type II diabetes: a randomized, controlled clinical trial.Lasers in medical science · 2014Trial
- The adjunctive effect of photodynamic therapy for residual pockets in single-rooted teeth: a randomized controlled clinical trial.Lasers in medical science · 2013Trial
- Microbiological Impact of Antimicrobial Photodynamic Therapy in Non-Surgical Periodontal Treatment.Pharmaceutics · 2025Review
- The Efficiency of Photodynamic Therapy in the Bacterial Decontamination of Periodontal Pockets and Its Impact on the Patient.Diagnostics (Basel, Switzerland) · 2022Article
- Susceptibility of oral bacteria to antibacterial photodynamic therapy.Journal of oral microbiology · 2019Article
- Curcumin photodynamic effect in the treatment of the induced periodontitis in rats.Lasers in medical science · 2017Article
- Increase in the nitric oxide release without changes in cell viability of macrophages after laser therapy with 660 and 808 nm lasers.Lasers in medical science · 2016Article
- An In Vitro Comparison of Antimicrobial Effects of Curcumin-Based Photodynamic Therapy and Chlorhexidine, on Aggregatibacter actinomycetemcomitans.Journal of lasers in medical sciences · 2016Article
- Effect of Antimicrobial Photodynamic Therapy as an Adjunct to Nonsurgical Treatment of Deep Periodontal Pockets: A Clinical Study.Journal of lasers in medical sciences · 2016Article
- Removal of black stains from teeth by photodynamic therapy: clinical and microbiological analysis.BMJ case reports · 2015Article
- Inactivation of Aggregatibacter actinomycetemcomitans by two different modalities of photodynamic therapy using Toluidine blue O or Radachlorin as photosensitizers: an in vitro study.Lasers in medical science · 2015Article
- Low-level diode laser therapy reduces lipopolysaccharide (LPS)-induced bone cell inflammation.Lasers in medical science · 2012Article
- Evaluation of antibacterial efficacy ofJournal of Indian Society of PeriodontologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Practitioners are not successful in implemented treatments due to the great difficulty in completely removing bacterial deposits and their endotoxins. This study aimed to evaluate the capacity of photodynamic therapy to reduce the numbers of viable bacteria in periodontal pockets. Microbiological samples were collected before and after scaling and after photodynamic therapy. Photodynamic therapy was performed through the insertion of the photosensitizer toluidine blue and Endo PTC into the pocket for 3 min, followed by photosensitization with low-intensity diode of 4 J/cm(2). The results (log(10)) were submitted to a descriptive analysis and a t-test. A reduction of 81.24% in the numbers of bacteria after scaling was observed, as well as 95.90% after photodynamic therapy (P < 0.01). Photodynamic therapy is indicated as an adjuvant treatment to reduce the numbers of viable bacteria in periodontal diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.