ReviewJournal of biosciences2009
Neurospora as a model fungus for studies in cytogenetics and sexual biology at Stanford.
Review in Journal of biosciences, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed.
- Review
- A DEAD-box RNA helicase mediates meiotic silencing by unpaired DNA.G3 (Bethesda, Md.) · 2023Article
- Regulator of G Protein Signaling Proteins Control Growth, Development and Cellulase Production inJournal of fungi (Basel, Switzerland) · 2022Article
- Molecular Mechanisms and Evolutionary Consequences of Spore Killers in Ascomycetes.Microbiology and molecular biology reviews : MMBR · 2021Review
- Mating Systems in True Morels (Microbiology and molecular biology reviews : MMBR · 2021Review
- Plasma Membrane Fusion Is Specifically Impacted by the Molecular Structure of Membrane Sterols During Vegetative Development ofGenetics · 2020Article
- Communicate and Fuse: How Filamentous Fungi Establish and Maintain an Interconnected Mycelial Network.Frontiers in microbiology · 2019Review
- Genetic relationships between the RACK1 homolog cpc-2 and heterotrimeric G protein subunit genes in Neurospora crassa.PloS one · 2019Article
- A-to-I RNA editing is developmentally regulated and generally adaptive for sexual reproduction inProceedings of the National Academy of Sciences of the United States of America · 2017Article
- The ancestral levels of transcription and the evolution of sexual phenotypes in filamentous fungi.PLoS genetics · 2017Article
- Article
- Seeing the world differently: variability in the photosensory mechanisms of two model fungi.Environmental microbiology · 2016Review
- Global gene expression and focused knockout analysis reveals genes associated with fungal fruiting body development in Neurospora crassa.Eukaryotic cell · 2014Article
- The Sclerotinia sclerotiorum mating type locus (MAT) contains a 3.6-kb region that is inverted in every meiotic generation.PloS one · 2013Article
- A putative transcription factor MYT2 regulates perithecium size in the ascomycete Gibberella zeae.PloS one · 2012Article
- Degeneration in codon usage within the region of suppressed recombination in the mating-type chromosomes of Neurospora tetrasperma.Eukaryotic cell · 2011Article
- Evolution of multicopper oxidase genes in coprophilous and non-coprophilous members of the order sordariales.Current genomics · 2011Article
- Meiotic regulators Ndt80 and ime2 have different roles in Saccharomyces and Neurospora.Genetics · 2010Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dodge's early work (1927-1940) on Neurospora genetics and sexual biology inspired Beadle and Tatum at Stanford to use N.crassa for their landmark discovery that genes specify enzymes. Neurospora has since become a model organism for numerous genetic, cytogenetic, biochemical, molecular and population biology studies. Neurospora is haploid in the vegetative phase with a transient diploid sexual phase. Its meiotic cells (asci) are large, allowing easy examination of dividing nuclei and chromosomes under a light microscope. The haploid meiotic products are themselves the sexual progeny that grow into vegetative cultures, thus avoiding the cumbersome testcrosses and complex dominance -recessive relationships, as in diploid organisms.The Perkins'laboratory at Stanford (1949-2007) played a pivotal role in advancing our knowledge of Neurospora genetics, sexual biology, cytogenetics and population biology. Since 1974, I have taken advantage of various chromosome-staining methods to examine ascus and ascospore development in wild type and in numerous mutant strains. In addition,I have used GFP-tagged genes to visualize the expression or silencing of unpaired genes in a post-transcriptional gene silencing process (meiotic silencing by unpaired DNA) that operates specifically during meiosis. The genome of N. crassa contains over 10 000 protein- coding genes. Gene knockouts or mutations in specific sequences may now be readily correlated with the observed cytological defects in the sexual stage, thus advancing our molecular understanding of complex processes during ascus and ascospore development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.