Trial reportJournal of lipid research2009
Measures of postprandial lipoproteins are not associated with coronary artery disease in patients with type 2 diabetes mellitus.
Trial report in Journal of lipid research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 23 citations in OpenAlex.
- Effect of combination therapy with fenofibrate and simvastatin on postprandial lipemia in the ACCORD lipid trial.Diabetes care · 2013Trial
- Cardiovascular disease in diabetes, beyond glucose.Cell metabolism · 2021Review
- Postprandial dyslipidemia in insulin resistant states in adolescent populations.Journal of biomedical research · 2020Article
- Fasting and postprandial lipid parameters: A comparative evaluation of cardiovascular risk assessment in prediabetes and diabetes.Journal of family medicine and primary care · 2020Article
- Effects of mipomersen, an apolipoprotein B100 antisense, on lipoprotein (a) metabolism in healthy subjects.Journal of lipid research · 2018Article
- Effects of PCSK9 Inhibition With Alirocumab on Lipoprotein Metabolism in Healthy Humans.Circulation · 2017Article
- Postprandial lipemia and the risk of coronary heart disease and stroke: the Atherosclerosis Risk in Communities (ARIC) Study.BMJ open diabetes research & care · 2017Article
- Peripheral arterial disease, type 2 diabetes and postprandial lipidaemia: Is there a link?World journal of diabetes · 2014Review
- Low density lipoprotein delays clearance of triglyceride-rich lipoprotein by human subcutaneous adipose tissue.Journal of lipid research · 2013Article
- Endothelial function in individuals with coronary artery disease with and without type 2 diabetes mellitus.Metabolism: clinical and experimental · 2010Article
- Postprandial lipoproteins and cardiovascular disease risk in diabetes mellitus.Current diabetes reports · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 1 institution in 1 country.
Funding
Abstract
Individuals with type 2 diabetes mellitus (DM) characteristically have elevated fasting and postprandial (PP) plasma triglycerides (TG). Previous case-control studies indicated that PPTG levels predict the presence of coronary artery disease (CAD) in people without DM; however, the data for patients with DM are conflicting. Therefore, we conducted a case-control study in DM individuals, 84 with (+) and 80 without (-) CAD. Our hypothesis was that DM individuals with or without CAD would have similar PPTG levels, but CAD+ individuals would have more small d<1.006 g/L lipoprotein particles. Several markers of PP lipid metabolism were measured over 10 h after a fat load. PP lipoprotein size and particle number were also determined. There was no significant difference in any measure of PP lipid metabolism between CAD+ and CAD-, except for apoB48, which was actually higher in CAD-. We followed 69 CAD- participants for a mean 8.7 years; 33 remained free of any cardiovascular event. There were no PP differences at baseline between these 33 who remained CAD- and either the 36 original CAD- who subsequently developed CAD or the original CAD+ group.PP measurements of TG-rich lipoproteins do not predict the presence of CAD in individuals with DM.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.