ArticleDevelopment (Cambridge, England)2009
Regulation of membrane trafficking and organ separation by the NEVERSHED ARF-GAP protein.
Article in Development (Cambridge, England), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
61 citing papers in PubMed, 121 citations in OpenAlex.
- The HAESA family of receptor-like kinases: abscission pathways and emerging functions.Frontiers in plant science · 2026Review
- Abscission zones: cellular interfaces for the programmed separation of organs.Annals of botany · 2025Review
- Abscission in plants: from mechanism to applications.Advanced biotechnology · 2024Review
- Dissection of the IDA promoter identifies WRKY transcription factors as abscission regulators in Arabidopsis.Journal of experimental botany · 2024Article
- Genetics of destemming in pepper: A step towards mechanical harvesting.Frontiers in genetics · 2023Article
- Extracellular vesiculo-tubular structures associated with suberin deposition in plant cell walls.Nature communications · 2022Article
- An Update on the Key Factors Required for Plant Golgi Structure Maintenance.Frontiers in plant science · 2022Review
- Article
- Multi-scale comparative transcriptome analysis reveals key genes and metabolic reprogramming processes associated with oil palm fruit abscission.BMC plant biology · 2021Article
- Expression Kinetics of Regulatory Genes Involved in the Vesicle Trafficking Processes Operating in Tomato Flower Abscission Zone Cells during Pedicel Abscission.Life (Basel, Switzerland) · 2020Article
- Petal abscission in fragrant roses is associated with large scale differential regulation of the abscission zone transcriptome.Scientific reports · 2020Article
- Genome wide association mapping and candidate gene analysis for pod shatter resistance in Brassica juncea and its progenitor species.Molecular biology reports · 2020Article
- Endosidin 2 accelerates PIN2 endocytosis and disturbs intracellular trafficking of PIN2, PIN3, and PIN4 but not of SYT1.PloS one · 2020Article
- Control of Organ Abscission and Other Cell Separation Processes by Evolutionary Conserved Peptide Signaling.Plants (Basel, Switzerland) · 2019Review
- The Yes and No of the Ethylene Involvement in Abscission.Plants (Basel, Switzerland) · 2019Review
- Transcriptional Regulation of Abscission Zones.Plants (Basel, Switzerland) · 2019Review
- HypermorphicPlant physiology · 2019Article
- GbSOBIR1 confers Verticillium wilt resistance by phosphorylating the transcriptional factor GbbHLH171 in Gossypium barbadense.Plant biotechnology journal · 2019Article
- Transcriptomic evidence for distinct mechanisms underlying abscission deficiency in the Arabidopsis mutants haesa/haesa-like 2 and nevershed.BMC research notes · 2018Article
- Members of the Arabidopsis FORKED1-LIKE gene family act to localize PIN1 in developing veins.Journal of experimental botany · 2018Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 1 institution in 1 country.
Funding
Abstract
Cell separation, or abscission, is a highly specialized process in plants that facilitates remodeling of their architecture and reproductive success. Because few genes are known to be essential for organ abscission, we conducted a screen for mutations that alter floral organ shedding in Arabidopsis. Nine recessive mutations that block shedding were found to disrupt the function of an ADP-ribosylation factor-GTPase-activating protein (ARF-GAP) we have named NEVERSHED (NEV). As predicted by its homology to the yeast Age2 ARF-GAP and transcriptional profile, NEV influences other aspects of plant development, including fruit growth. Co-localization experiments carried out with NEV-specific antiserum and a set of plant endomembrane markers revealed that NEV localizes to the trans-Golgi network and endosomes in Arabidopsis root epidermal cells. Interestingly, transmission electron micrographs of abscission zone regions from wild-type and nev flowers reveal defects in the structure of the Golgi apparatus and extensive accumulation of vesicles adjacent to the cell walls. Our results suggest that NEV ARF-GAP activity at the trans-Golgi network and distinct endosomal compartments is required for the proper trafficking of cargo molecules required for cell separation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.