ArticleBehavioural processes2009
Nicotine-evoked conditioned responding is dependent on concentration of sucrose unconditioned stimulus.
Article in Behavioural processes, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Cigarette Smoke Extract and Nicotine Evoke Similar Interoceptive Effects in a Pavlovian Occasion Setting Task in Male and Female Sprague-Dawley Rats.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026Article
- The inside story: Interoceptive Pavlovian conditioning with the nicotine stimulus.Journal of experimental psychology. Animal learning and cognition · 2025Review
- Use of the overexpectation effect to reduce conditioned seeking behavior controlled by nicotine.Psychonomic bulletin & review · 2024Article
- Double dissociation of the anterior and posterior dorsomedial caudate-putamen in the acquisition and expression of associative learning with the nicotine stimulus.Neuropharmacology · 2017Article
- The effect of sazetidine-A and other nicotinic ligands on nicotine controlled goal-tracking in female and male rats.Neuropharmacology · 2017Article
- The effect of switching pharmacological intervention during extinction on nicotine-evoked conditioned responding in rats.Psychopharmacology · 2015Article
- Interoceptive conditioning with nicotine using extinction and re-extinction to assess stimulus similarity with bupropion.Neuropharmacology · 2014Article
- Interoceptive conditioning in rats: effects of using a single training dose or a set of 5 different doses of nicotine.Pharmacology, biochemistry, and behavior · 2013Article
- Nicotine increases sucrose self-administration and seeking in rats.Addiction biology · 2012Article
- Conditioned response evoked by nicotine conditioned stimulus preferentially induces c-Fos expression in medial regions of caudate-putamen.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2012Article
- An examination of NMDA receptor contribution to conditioned responding evoked by the conditional stimulus effects of nicotine.Psychopharmacology · 2011Article
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Authors and funding
3 authors.
Funding
Abstract
Previous studies have shown that the interoceptive nicotine conditional stimulus (CS) functions similarly to exteroceptive CSs such as lights or environments. For instance, the appetitive conditioned response (CR) evoked when nicotine is repeatedly paired with sucrose presentations (the unconditioned stimulus; US) is sensitive to changes in training dose (CS salience) and the contiguity between the CS effects and sucrose. The current study was conducted to extend this research by examining the possible role of US intensity in CR acquisition and maintenance. Rats were trained using one of four sucrose concentrations: 0, 4, 16, or 32% (w/v). On nicotine sessions (0.4 mg base/kg), rats received 36 deliveries (4s each) of their assigned concentration intermittently throughout the session; sucrose was withheld on saline sessions. In all groups, an appetitive goal-tracking CR was acquired at a similar rate. However, the asymptotic CR level varied with sucrose concentration. The magnitude of the CR was increased in rats trained with higher sucrose US concentrations. These findings are consistent with previous Pavlovian conditioning research, and extend the conditions under which the nicotine state functions as an interoceptive conditional stimulus.
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