ArticleThe Journal of the Acoustical Society of America2009
Material properties from acoustic radiation force step response.
Article in The Journal of the Acoustical Society of America, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed.
- Sono-Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Combining Spatial Registration With Clutter Filtering for Power-Doppler Imaging in Peripheral Perfusion Applications.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2022Article
- Optical coherence elastography - OCT at work in tissue biomechanics [Invited].Biomedical optics express · 2017Review
- Indentation Analysis of Biphasic Viscoelastic Hydrogels.Mechanics of materials : an international journal · 2016Article
- Optical coherence elastography for tissue characterization: a review.Journal of biophotonics · 2015Review
- A Review of Vibro-acoustography and its Applications in Medicine.Current medical imaging reviews · 2011Article
- Acoustic radiation force-based elasticity imaging methods.Interface focus · 2011Article
- Spectroscopic optical coherence elastography.Optics express · 2010Article
- Dynamic spectral-domain optical coherence elastography for tissue characterization.Optics express · 2010Article
- Acoustomotive optical coherence elastography for measuring material mechanical properties.Optics letters · 2009Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
An ultrasonic technique for estimating viscoelastic properties of hydrogels, including engineered biological tissues, is being developed. An acoustic radiation force is applied to deform the gel locally while Doppler pulses track the induced movement. The system efficiently couples radiation force to the medium through an embedded scattering sphere. A single-element, spherically-focused, circular piston element transmits a continuous-wave burst to suddenly apply and remove a radiation force to the sphere. Simultaneously, a linear array and spectral Doppler technique are applied to track the position of the sphere over time. The complex shear modulus of the gel was estimated by applying a harmonic oscillator model to measurements of time-varying sphere displacement. Assuming that the stress-strain response of the surrounding gel is linear, this model yields an impulse response function for the gel system that may be used to estimate material properties for other load functions. The method is designed to explore the force-frequency landscape of cell-matrix viscoelasticity. Reported measurements of the shear modulus of gelatin gels at two concentrations are in close agreement with independent rheometer measurements of the same gels. Accurate modulus measurements require that the rate of Doppler-pulse transmission be matched to a priori estimates of gel properties.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.