ArticleAge (Dordrecht, Netherlands)2008
Level of CD14+-endothelial progenitor cells is not associated with coronary artery disease or cardiovascular risk factors.
Article in Age (Dordrecht, Netherlands), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 6 citations in OpenAlex.
- Assessment of Serum Neopterin as a Biomarker in Peripheral Artery Disease.Diagnostics (Basel, Switzerland) · 2021Article
- From top to bottom: midkine and pleiotrophin as emerging players in immune regulation.Journal of leukocyte biology · 2017Review
- Age and Human Regenerative Capacity Impact of Cardiovascular Risk Factors.Circulation research · 2016Article
- Circulating Progenitor Cells Identify Peripheral Arterial Disease in Patients With Coronary Artery Disease.Circulation research · 2016Article
- Endothelial progenitor cells: a new player in lupus?Arthritis research & therapy · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is evidence for two subpopulations among circulating endothelial progenitor cells (EPCs), i.e., CD34(+)-EPCs and CD14(+)-EPCs. Prior studies on the relationship between the level of EPCs and coronary artery disease (CAD), either did not distinguish between the two types of EPCs or studied only CD34(+)-EPCs. We therefore investigated whether the number of circulating CD14(+)-EPCs correlates with either CAD and/or cardiovascular risk factors. Circulating CD14(+)-EPCs-as defined by the surface markers CD14(+)KDR(+)-were analyzed by flow cytometry in 100 individuals [34 control subjects, 41 patients with stable CAD and 25 patients with acute coronary syndromes (ACS)]. The level of circulating CD14(+)-EPCs was not significantly different in patients with normal coronary arteries compared to those with stable CAD or ACS. Neither was there any association between the severity of CAD or risk factors and the number of circulating CD14(+)-EPCs. Thus, the number of circulating CD14(+)-EPCs was not significantly correlated either with the severity of coronary disease or with cardiovascular risk factors.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.