Evidence map›Paper›PMID 19424455›Full record

ArticleProceedings. IEEE International Symposium on Biomedical Imaging2007

AUTOMATIC STRUCTURE INTERPRETATION OF SINGLE PARTICLE CRYO-ELECTRON MICROSCOPY: FROM IMAGES TO PSUEDO-ATOMIC MODELS.

Chandrajit L Bajaj

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings. IEEE International Symposium on Biomedical Imaging, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Chandrajit L BajajDepartment of Computer Sciences & Institute of Computational Engineering and Sciences, University of Texas at Austin, Austin, Texas 78712.
The University of Texas at Austin · US

Funding

VISUALIZATION TOOLS FOR AUTOMATED MOLECULAR MICROSCOPYP41RR008605 · NCRR · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI OLSON, ARTHUR J. · 1994 to 2011
$28.1M
ZERNIKE PHASE PLATE CRYOEM IN OKAZAKIP41RR002250 · NCRR · UNIVERSITY OF ARIZONA · PI CHIU, WAH · 1985 to 2011
$22.1M
TOWARD A COMPUTATION CENTER FOR BIOMOLECULAR COMPLEXES: STRUCTURAL BIOLOGYP20RR020647 · NCRR · BAYLOR COLLEGE OF MEDICINE · PI CHIU, WAH · 2004 to 2006
$1.8M
A New Approach to Rapid Protein-Protein DockingR01GM073087 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI BAJAJ, CHANDRAJIT L · 2006 to 2008
$1.3M
Software Maintenance for Biomolecular ComplexesR01EB004873 · NIBIB · UNIVERSITY OF TEXAS AT AUSTIN · PI BAJAJ, CHANDRAJIT L · 2007 to 2010
$1.2M
Hierarchical Methods for Large BioMolecular ComplexesR01GM074258 · NIGMS · UNIVERSITY OF TEXAS AUSTIN · PI BAJAJ, CHANDRAJIT L · 2005 to 2010
$778k
NCRR NIH HHS P20 RR020647NCRR NIH HHS P41 RR002250NCRR NIH HHS P41 RR008605NIBIB NIH HHS R01 EB004873NIGMS NIH HHS R01 GM073087NIGMS NIH HHS R01 GM074258
6 · The paper itself

Abstract

Three dimensional Electron Microscopy (EM) and in particular single particle reconstruction using cryo-EM, has rapidly advanced over recent years, such that increasingly several macromolecular complexes can be resolved at subnanometer resolution (6-10 Å). This paper reviews some of the main volumetric image and geometric post-processing steps once a three dimensional EM map (henceforth a 3D map) has been reconstructed from single particle Cryo-EM, as essential steps in an enhanced and automated computational structure interpretation pipeline. In particular the paper addresses automated filtering, critical point calculations, symmetric and non-symmetric molecular domain segmentation, molecular surface selection, curation, and protein secondary structure (α- helices and β-sheets) elucidation from 3D maps.

Identifiers

PMID19424455
PMCPMC2678009
OpenAlexW2123729061

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.