ArticleJournal of clinical outcomes management : JCOM2008
Optimizing Medication Adherence in Older Patients: A Systematic Review.
Article in Journal of clinical outcomes management : JCOM, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A Systematic Review of Compensation and Technology-Mediated Strategies to Maintain Older Adults' Medication Adherence.International journal of environmental research and public health · 2023Pooled it
- Effectiveness of clinical pharmacy services: an overview of systematic reviews (2000-2010).International journal of clinical pharmacy · 2015Pooled it
- Improving post-discharge medication adherence in patients with CVD: a pilot randomized trial.Arquivos brasileiros de cardiologia · 2014Trial
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- Article
- Effectiveness of healthcare educational and behavioral interventions to improve gout outcomes: a systematic review and meta-analysis.Therapeutic advances in musculoskeletal disease · 2018Review
- Collaborative intervention between pharmacists and physicians on elderly patients: a randomized controlled trial.Therapeutics and clinical risk management · 2018Article
- Effect of pharmaceutical care on medication adherence and hospital admission in patients with chronic obstructive pulmonary disease (COPD): a randomized controlled study.Journal of thoracic disease · 2014Article
- Sex differences in barriers to antihypertensive medication adherence: findings from the cohort study of medication adherence among older adults.Journal of the American Geriatrics Society · 2013Article
- Adverse drug events as a cause of hospitalization in older adults.Drug safety · 2012Review
- Measuring and improving adherence to osteoporosis pharmacotherapy.Current opinion in rheumatology · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
objectiveTo review the literature on strategies to optimize medication adherence in community-dwelling older adults and to make recommendations for clinical practice.
methodsA systematic literature search was conducted using the MEDLINE, CINAHL, PsycINFO, International Pharmaceutical Abstracts, and EMBASE databases for randomized controlled trials examining strategies to optimize medication adherence in patients aged 65 or older prescribed long-term medication regimens. Additional studies were found by examining the reference lists of systematic reviews and selected papers. 34 papers reporting on 33 studies met the eligibility criteria and were included in this review.
resultsImprovement in adherence was mixed across the studies examining educational interventions, with only 12 of the 28 studies showing improvement in adherence; most were delivered by pharmacists. Effect sizes for the statistically significant educational interventions ranged from Cohen's d = 0.14 to 4.93. Four of the 5 interventions using memory aids and cues, some in conjunction with newer technologies, improved adherence. Effect sizes for the statistically significant interventions using memory aids and cues ranged from Cohen's d = 0.26 to 2.72.
conclusionThe evidence from this review does not clearly support one single intervention to optimize medication adherence in older patients. Future studies should explore suggestive strategies, such as tailored interventions involving ongoing contact, and should endeavor to correct methodologic weaknesses found in the literature.
Identifiers
19424450PMC2677827What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.