Evidence map›Paper›PMID 19423627›Full record

ArticleMicrobiology (Reading, England)2009

Population structure of Streptococcus oralis.

Thuy Do, Keith A Jolley, Martin C J Maiden, Steven C Gilbert, Douglas Clark, William G Wade, David Beighton

Abstract read
In one paragraph

Article in Microbiology (Reading, England), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Article
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  7. Article
  8. Selective Inhibition ofAdvanced materials interfaces · 2020
    Article
  9. Article
  10. Article
  11. Is the Oral Microbiome Associated with Blood Pressure in Older Women?High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2019
    Article
  12. Article
  13. Quantification of Human Oral and FecalFrontiers in microbiology · 2019
    Article
  14. Preseptal Cellulitis in Children: A Single-Center Experience.Sisli Etfal Hastanesi tip bulteni · 2019
    Article
  15. Observational
  16. Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Thuy DoBiomedical Research Centre, Guy's and St Thomas' Hospital NHS Foundation Trust, London SE1 9RT, UK.
Keith A JolleyDepartment of Zoology, University of Oxford, Oxford OX1 3PS, UK.
Martin C J MaidenDepartment of Zoology, University of Oxford, Oxford OX1 3PS, UK.
Steven C GilbertBiomedical Research Centre, Guy's and St Thomas' Hospital NHS Foundation Trust, London SE1 9RT, UK.
Douglas ClarkKing's College London Dental Institute at Guy's, King's College and St Thomas' Hospitals, Infection Research Group, Guy's Campus, London SE1 9RT, UK.
William G WadeKing's College London Dental Institute at Guy's, King's College and St Thomas' Hospitals, Infection Research Group, Guy's Campus, London SE1 9RT, UK.
David BeightonBiomedical Research Centre, Guy's and St Thomas' Hospital NHS Foundation Trust, London SE1 9RT, UK.

Funding

Wellcome Trust 087622Wellcome Trust GR076381
6 · The paper itself

Abstract

Streptococcus oralis is a member of the normal human oral microbiota, capable of opportunistic pathogenicity; like related oral streptococci, it exhibits appreciable phenotypic and genetic variation. A multilocus sequence typing (MLST) scheme for S. oralis was developed and the resultant data analysed to examine the population structure of the species. Analysis of 113 isolates, confirmed as belonging to the S. oralis/mitis group by 16S rRNA gene sequencing, characterized the population as highly diverse and undergoing inter- and intra-species recombination with a probable clonal complex structure. ClonalFrame analysis of these S. oralis isolates along with examples of Streptococcus pneumoniae, Streptococcus mitis and Streptococcus pseudopneumoniae grouped the named species into distinct, coherent populations and did not support the clustering of S. pseudopneumoniae with S. mitis as reported previously using distance-based methods. Analysis of the individual loci suggested that this discrepancy was due to the possible hybrid nature of S. pseudopneumoniae. The data are available on the public MLST website (http://pubmlst.org/soralis/).

Indexed as

Genetic VariationDNA, BacterialGenes, BacterialHumansMouthPhylogenyRecombination, GeneticRNA, Ribosomal, 16SSequence Analysis, DNASpecies SpecificityStreptococcal InfectionsStreptococcus mitisStreptococcus oralisStreptococcus pneumoniaeDNA, BacterialRNA, Ribosomal, 16S

Identifiers

PMID19423627
PMCPMC2885674

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.