Evidence map›Paper›PMID 19423025›Full record

ArticleGastrointestinal endoscopy clinics of North America2009

Targeted endoscopic imaging.

Meng Li, Thomas D Wang

Abstract read
In one paragraph

Article in Gastrointestinal endoscopy clinics of North America, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Imaging Inflammation and Infection in the Gastrointestinal Tract.International journal of molecular sciences · 2019
    Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Molecular imaging in gastroenterology.Nature reviews. Gastroenterology & hepatology · 2013
    Review
  10. Review
  11. Article
  12. Article
  13. Future and advances in endoscopy.Journal of biophotonics · 2011
    Review
  14. Article
  15. Article
  16. Review
  17. Molecular endoscopic imaging: the future is bright.Therapeutic advances in gastrointestinal endoscopy
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Meng LiDepartment of Medicine, University of Michigan School of Medicine, Ann Arbor, 48109, USA.
Thomas D Wang

Funding

Novel Confocal Microscope for Molecular/Cellular ImagingK08DK067618 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WANG, THOMAS D · 2003 to 2007
$607k
NCI NIH HHS R03 CA096752NIDDK NIH HHS K08 DK067618
6 · The paper itself

Abstract

Endoscopy has undergone explosive technological growth in recent years, and with the emergence of targeted imaging, its truly transformative power and impact on medicine lies just over the horizon. Today, our ability to see inside the digestive tract with medical endoscopy is headed toward exciting crossroads. The existing paradigm of making diagnostic decisions based on observing structural changes and identifying anatomic landmarks may soon be replaced by visualizing functional properties and imaging molecular expression. In this novel approach, the presence of intracellular and cell surface targets unique to disease are identified and used to predict the likelihood of mucosal transformation and response to therapy. This strategy could result in the development of new methods for early cancer detection, personalized therapy, and chemoprevention. This targeted approach will require further development of molecular probes and endoscopic instruments, and will need support from the US Food and Drug Administration for streamlined regulatory oversight. Overall, this molecular imaging modality promises to significantly broaden the capabilities of the gastroenterologist by providing a new approach to visualize the mucosa of the digestive tract in a manner that has never been seen before.

Indexed as

Cell Transformation, NeoplasticMolecular Diagnostic TechniquesEndoscopy, GastrointestinalGastrointestinal NeoplasmsGene Expression Regulation, NeoplasticHumansIntestinal MucosaPrecancerous ConditionsSensitivity and Specificity

Identifiers

PMID19423025
PMCPMC3217463

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.